Citrullus colocynthis | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

Back to previous

Download a full report in PDF format

Common name(s)

Colocynth

How used

Medicinal

Data Views

Activities: 389

Chemicals w/Activities: 42

All Chemicals: 74

CSV Excel PDF

Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
Click on column headings to sort table by that column
# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	1,26-HEXACOSANOL	Fruit	--	--	--	*
0	10,13-DIMETHYLPENTA-13-DECEN-1-AL	Petiole	--	--	--	*
10	ALPHA-AMYRIN	Seed	--	--	--	*
Analgesic * Antiedemic IC43=40 mg/kg ipr rat * Antiinflammatory IC71=1,000 ppm orl * Antinociceptive * Antitumor * Antiulcer * Cytotoxic 50-400 * Gastroprotective * Hepatoprotective * Insectifuge *
0	ALPHA-ELATERIN	Fruit	--	--	--	*
0	ALPHA-ELATERIN-2-D-GLYCOPYRANOSIDE	Stem	--	1700.0	--	*
0	ALPHA-ELATERIN-2-D-GLYCOPYRANOSIDE	Petiole	--	800.0	--	*
0	ALPHA-ELATERIN-2-D-GLYCOPYRANOSIDE	Root	--	490.0	--	*
0	ALPHA-ELATERIN-2-D-GLYCOPYRANOSIDE	Fruit	--	2000.0	--	*
0	ALPHA-ELATERIN-2-D-GLYCOPYRANOSIDE	Seed	--	1800.0	--	*
0	ALPHA-ELATERIN-2-D-GLYCOPYRANOSIDE	Leaf	--	1500.0	--	*
0	ALPHA-MANNITOL	Pericarp	--	6000.0	--	*
2	ALPHA-SPINASTEROL	Fruit	--	--	--	*
Antiinflammatory >Phenylbutazone * Antipyretic *
36	ANETHOLE	Petiole	--	--	--	*
Allergenic * Antibacterial MBC=200 ug/ml * Antigenotoxic 40-400 mg/kg orl mus * Antihepatotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * AntiNF-kB * Antioxidant * Antiradicular * Antisalmonella MIC=200 ug/ml * Antiseptic 200 ug/ml * Antispasmodic * AntiTNF * Antitumor * Antiyeast * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide * Carminative Merck 11th Edition Dermatitigenic * Digestive Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. Estrogenic Australian J. Med Herbalism, 7: 29. Expectorant Martindale's 29th Fungicide Wolf, R.B. Effects Of p-Methoxycinnamaldehyde From Star Anise And Related Cinnamic Acid Derivatives On Velvetleaf Germination. Journal of Natural Products, 49(1): 156-158, 1986. Gastrostimulant * Hepatotoxic 695 mg/kg orl mus/days Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Immunostimulant Economic & Medicinal Plant Research, 1: 124. Insecticide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. Lactagogue * Leucocytogenic Economic & Medicinal Plant Research, 1: 124. Mutagenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Nephroprotective Toxicol Appl. Pharmacol. 1996. Pesticide * Secretogogue Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Secretolytic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Sweetener 13 x sucrose * Sympathomimetic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
7	ANISALDEHYDE	Petiole	--	--	--	*
Antimutagenic Economic & Medicinal Plant Research, 6: 235. Fungicide * Insecticide Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Pesticide * Tyrosinase-Inhibitor ID50=320 uM * Tyrosinase-Inhibitor ID50=0.32 mM * Tyrosinase-Inhibitor ID50=380-970 uM *
0	ARACHIDIC-ACID	Seed	--	--	--	*
112	ASCORBIC-ACID	Fruit	--	122.0	-0.28	*
Acidulant FEMA 6,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Aldose-Reductase-Inhibitor Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Analgesic 5-10 g/day * Angiotensin-Receptor-Blocker * AntiAGE 2,000 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaggregant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaging 400 mg/day * Antiallergic * Antialzheimeran 2,000-6,000 mg/day * Antiarthritic 0.2-1 g/day * Antiasthmatic 1,000 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiatherosclerotic * Antibacterial Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anticataract 1 g 3x/day * Anticataract 350 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticataract 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Anticervicaldysplasic 1,000-2,000 mg/day * AntiCFS 500-1,000 mg * Anticlimacteric 500-5,000 mg/day * Anticold 1-2 g/man/day * AntiCrohn's 50-100 mg/day/orl/man Martindale's 29th AntiCTS 1,000 mg 3x/day * Antidecubitic 500 mg/man/2x/day Martindale's 28th Antidementia * Antidepressant 2,000 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antidiabetic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antidote (Aluminum) Economic & Medicinal Plant Research, 6: 189. Antidote (Cadmium) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Paraquat) Martindale's 28th Antieczemic 3.5-5 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiedemic 1 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiencephalitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiendometriotic 2,000 mg/day * Antifatigue 500-1,000 mg * Antifibrotic 1,000-2,000 mg * Antigallstone 1,000-3,000 mg/day * Antigastritic * Antigingivitic * Antiglaucomic 2 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antihangover 1,000 mg * Antihemorrhagic 1 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihepatitic 2-6 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihepatotoxic Economic & Medicinal Plant Research, 6: 189. Antiherpetic 1-5 g/day * Antihistaminic 2 g/day orl man * Antihypertensive * Antiinfertility 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiinflammatory Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antilepric 1.5 g/man/day Martindale's 28th Antilithic 1,000-3,000 mg/day * AntiLyme 500-2,000 mg * Antimaculitic * Antimeasles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 500-5,000 mg/day * Antimigraine Martindale's 29th Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antineuramidase * Antinitrosic 1 g/man/day Martindale's 28th Antiobesity 1 g 3x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiorchitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiosteoarthritic 1 g 2x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic 500 mg/day * Antioxidant 100 ppm * Antiparkinsonian 1 g 2-3x/day * Antiparotitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiperiodontitic 1 g 2x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antipneumonic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antipodriac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antipoliomyelitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antipyretic Economic & Medicinal Plant Research, 6: 189. Antiradicular Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 AntiRaynaud's 500 mg 1-2x/day * Antiretinotic * Antirheumatic * Antirhinitic 1,000 mg 3x/day * Antiscorbutic 10 mg/man/day Martindale's 28th Antiseptic MIC=3.3-217 mg/ml Martindale's 28th Antiseptic 4-8 g/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antishingles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antispasmodic 500-5,000 mg/day * Antistress 500-1,000 mg * Antisyndrome-X 1-4 g/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antitumor (Gastric) * Antitumor (Lung) * Antiulcer * Antiviral 1-5 g/day * Apoptotic 1-10 mM * Asthma-preventive 1,000 mg/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Beta-Adrenergic Receptor Blocker * Beta-Glucuronidase-Inhibitor 1.5 g/day/man * Calcium-Antagonist * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective * Cold-preventive 1-2 g/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Collagenic * Detoxicant * Diuretic 700 mg/man/orl * Fistula-Preventive Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Hypocholesterolemic 300-1,000 mg/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Hypoglycemic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypotensive 1,000 mg/man/day * Immunomodulator * Immunostimulant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Interferonogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Lithogenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Mucolytic 1 g/woman/day Martindale's 28th Pesticide * Uricosuric 4 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Urinary-Acidulant Martindale's 29th Vasodilator * Vulnerary Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
0	ASPARAGININE	Flower	--	--	--	*
9	BENZYL-ALCOHOL	Petiole	--	--	--	*
Allergenic Martindale's 29th Anesthetic Martindale's 28th Antiodontalgic Martindale's 28th Antipruritic * Antiseptic Martindale's 29th FLavor Fema 200-1,200 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide * Pesticide * Sedative Jim Duke's personal files.
47	BETA-SITOSTEROL	Plant	--	--	--	*
Androgenic * Angiogenic * Anorexic Martindale's 28th Antiadenomic Merck 11th Edition Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Anticancer (Cervix) * Anticancer (Lung) * Antiedemic IC54=320 mg/kg orl * Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * Antileukemic * Antilymphomic * Antimutagenic 250 ug/ml * Antiophidic 2.3 mg mus Economic & Medicinal Plant Research, 5: 363. Antioxidant IC44=10 uM * Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antiprostaglandin 30 mg/day/12 wks * Antiprostatadenomic Merck 11th Edition Antiprostatitic 10-20 mg 3 x/day/orl man * Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Antitumor (Cervix) * Antitumor (Lung) * Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991. Apoptotic * Artemicide LC50=110 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Caspase-8-Inducer * Estrogenic * Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Hepatoprotective * Hypocholesterolemic 2-6 g/man/day/orl Martindale's 30th Hypocholesterolemic 9-3,330 mg/man/day/orl Martindale's 28th Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypolipidemic 2-6 g/day * Pesticide * Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Ulcerogenic 500 mg/kg ipr rat *
6	BETA-SITOSTEROL-D-GLUCOSIDE	Plant	--	--	--	*
Antispasmodic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antitumor * CNS-Depressant Rizk, A.F.M. and Al-Nowaihi, A.S., The Phytochemistry of the Horticultural Plants of Qatar, Scientific and Applied Research Centre, University of Qatar. CNS-Stimulant * Convulsant * Hypoglycemic *

List of all activity chemical
Click on column headings to sort table by that column
# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

Show all rows.

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Citrullus colocynthis (Cucurbitaceae)

Data Views