Canarium indicum | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Java-Olive, Manila Elemi

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Food

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Activities: 196

Chemicals w/Activities: 22

All Chemicals: 35

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
67	1,8-CINEOLE	Essential Oil	2500.0	6250.0	-0.77	*
(-)-Chronotropic 87 nl/ml Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. (-)-Inotropic 87 nl/ml Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Acaricide LC100=6 uM * Allelopathic * Allergenic * Anesthetic * Anthelmintic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiacetylcholinesterase IC50=41 ug/ml * Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569. Antibacterial 50 ppm * Antibronchitic * Anticariogenic * Anticatarrh Martindale's 29th Anticholinesterase IC50=50-70 * Antifatigue * Antihalitosic American Health, 12(4): 17, 1993. Antiinflammatory * Antilaryngitic * Antinociceptive * Antipharyngitic * Antiplaque * Antirheumatic * Antirhinitic * Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antisinusitic * Antispasmodic * Antistaphylococcic 50 ppm * Antitussive * Antiulcer * Candidicide * Carcinogenic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Choleretic * CNS-Stimulant * Convulsant * Counterirritant Martindale's 29th Cytochrome-P450-Inducer * Decongestant * Degranulant 0.3 ul/ml * Dentifrice Martindale's 29th Edemagenic inj * Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. FLavor FEMA 1-200 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide * Gastroprotective * Gram(+)icide * Gram(-)icide * Hepatotonic * Herbicide IC50=78 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Hypotensive * Inflammatory inj * Insectifuge * Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Neurotoxic * P450-Inducer * Pediculicide 2.3 x pyrethrin * Perfume Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Rubefacient Martindale's 29th Secretogogue * Sedative * Spasmogenic * Surfactant * Testosterone-Hydroxylase-Inducer * Transdermal * Trichomonicide LD100=1,000 ug/ml *
2	ALPHA-HUMULENE	Essential Oil	100.0	250.0	-0.48	*
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
11	ALPHA-PHELLANDRENE	Essential Oil	15100.0	37750.0	0.14	*
Antibacterial Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Dermal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Emetic * FLavor FEMA 10-130 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Insectiphile Pakistan Encyclopedia Planta Medica. 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Laxative * Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
28	ALPHA-PINENE	Essential Oil	400.0	1000.0	-0.55	*
Allelochemic * Allergenic * Antiacne * Antibacterial * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory 500 mg/kg * Antipneumonic * Antiseptic * Antispasmodic * Antistaphylococcic * Antiviral Economic & Medicinal Plant Research, 5: 195. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Coleoptophile * Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. FLavor FEMA 15-150 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide IC50=30 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insecticide 0.82 uM/fly * Insectifuge 50 ppm * Insectiphile J. Stored. Prod. Res., 22:141, 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. P450-2B1-Inhibitor IC50=0.087 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Sedative Lawrence Review of Natural Products, Jun-90. Spasmogenic * Tranquilizer Lawrence Review of Natural Products, Jun-90. Transdermal *
1	AMYRIN	Gum	--	--	--	*
Antitumor *
36	ANETHOLE	Plant	34000.0	85000.0	--	*
Allergenic * Antibacterial MBC=200 ug/ml * Antigenotoxic 40-400 mg/kg orl mus * Antihepatotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * AntiNF-kB * Antioxidant * Antiradicular * Antisalmonella MIC=200 ug/ml * Antiseptic 200 ug/ml * Antispasmodic * AntiTNF * Antitumor * Antiyeast * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide * Carminative Merck 11th Edition Dermatitigenic * Digestive Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. Estrogenic Australian J. Med Herbalism, 7: 29. Expectorant Martindale's 29th Fungicide Wolf, R.B. Effects Of p-Methoxycinnamaldehyde From Star Anise And Related Cinnamic Acid Derivatives On Velvetleaf Germination. Journal of Natural Products, 49(1): 156-158, 1986. Gastrostimulant * Hepatotoxic 695 mg/kg orl mus/days Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Immunostimulant Economic & Medicinal Plant Research, 1: 124. Insecticide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. Lactagogue * Leucocytogenic Economic & Medicinal Plant Research, 1: 124. Mutagenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Nephroprotective Toxicol Appl. Pharmacol. 1996. Pesticide * Secretogogue Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Secretolytic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Sweetener 13 x sucrose * Sympathomimetic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
0	ASH	Seed	--	38500.0	-0.28	*
3	BETA-PHELLANDRENE	Essential Oil	800.0	2000.0	-1.07	*
Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Fungicide Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Perfumery Merck 11th Edition
0	BREIN	Gum	--	--	--	*
19	CARVONE	Plant	200.0	500.0	-0.35	*
Allergenic * Antiacetylcholinesterase IC50=1.4-1.8 mM * Antiproliferative * Antiseptic 1.5 x phenol Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidistat * Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. CNS-Stimulant * FLavor FEMA 80-3,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungistat * Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Trichomonicide LD100=300 ug/ml * Vermicide *
0	CARVOTANACETONE	Essential Oil	100.0	250.0	--	*
7	DIPENTENE	Gum	--	--	--	*
Allergenic * Antibacterial Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antiviral Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sedative Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	ELEMADIENOLIC-ACID	Gum	--	--	--	*
0	ELEMADIENONIC-ACID	Gum	--	--	--	*
16	ELEMICIN	Essential Oil	3500.0	8750.0	-1.00	*
Antiaggregant IC50=360 uM Janssens, J., Laekeman, G.M., Pieters, L.A.C., Totte, J., Herman, A.G., and Vlietinck, A.J. 1990. Nutmeg Oil: Identification and Quantitation of its Most Active Constituents as Inhibitors of Platelet Aggregation. J.of Ethnopharmacology, 29: 179-188, 1990. Antidepressant ihl Jim Duke's personal files. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antihistaminic * Antiserotonic Internat. J. Oriental Med. 15(4): 199, 1990+ Antistress ihl Jim Duke's personal files. DNA-Binder Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Fungicide MIC=8 ug * Hallucinogenic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Hypotensive ihl Jim Duke's personal files. Insecticide 100 ppm * Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Larvicide 100 ppm * Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Pesticide * Schistosomicide Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
2	ELEMOL	Essential Oil	15000.0	37500.0	1.00	*
Antiacetylcholinesterase IC50=34 ug/ml * Antiulcer *
0	EO	Gum	100000.0	250000.0	-0.27	*
0	FAT	Seed	--	728400.0	2.44	*
11	GAMMA-TERPINENE	Essential Oil	400.0	1000.0	-0.81	*
Acaricide * ACE-Inhibitor 100 ug/ml (weak activity) * Aldose-Reductase-Inhibitor 100 ug/ml Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. Antiacetylcholinesterase IC23=1.2 mM * Antifeedant Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. Antioxidant Jim Duke's personal files. FLavor FEMA 1-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide *
60	LIMONENE	Essential Oil	54100.0	135250.0	0.04	*
Acaricide LC100=8 uM * AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8. Allelochemic * Allergenic 1/20th carene * Antiacetylcholinesterase IC22-26=1.2 mM * Antiadenomic * Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8. Antiasthmatic * Antibacterial Revista Itiliana Eppos, 12: 5, 1994. Anticancer * Antiesophagitic * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory * Antilithic * Antilymphomic * Antimetastatic (Stomach) * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antiobesity * Antiseptic * Antispasmodic ED50=0.197 mg/ml Fitoterapia No.59-1984. Antitumor * Antitumor (Breast) * Antitumor (Colon) * Antitumor (Pancreas) * Antitumor (Prostate) * Antitumor (Stomach) * Antiviral * Apoptotic * Bronchoprotectant * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidistat * Chemopreventive * Cholesterolytic * Detoxicant * Enterocontractant J. Aromatherapy 4: 22. Expectorant * FLavor * Fungiphilic J. Agric. Food Chem. 43: 2283. Fungistat * GST-Inducer * Herbicide IC50=45 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Histaminic * Immunomodulator * Insecticide 0.37 uM/fly * Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Interleukin-6-Inhibitor * Irritant * Lipolytic * Myorelaxant 50 mg/kg * Nematicide IC=100 ug/ml Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. NO-Genic * Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet) * Ozone-Scavenger * P450-Inducer * Peristaltic * Pesticide * Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. Sedative ED=1-32 mg/kg Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Transdermal *

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Canarium indicum (Burseraceae)

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