Alangium lamarckii | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Activities: 32

Chemicals w/Activities: 7

All Chemicals: 17

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	1',2'-DEHYDROTUBULOSINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
0	10-O-DEMETHYLCEPHAELINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
0	2'-N-(1''-DEOXY-1''-BETA-D-FRUCTOPYRANOSYL)-CEPHAELINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
0	ALANGINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
0	ALANGISIDE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
13	BETULIN	Seed	--	2222.2	--	Jim Duke's personal files.
Anticarcinomic * Antifeedant * Antiflu * AntiHIV 6.1 uM * Antiinflammatory Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas. Planta Medica, 61: 9. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiviral 6.1 uM Aphidifuge Lugemwa, F.N., Huang, F-Y., Bentley, M.D., Mendel, M.J., and Alford, A.R. 1990. A Heliothis zea Antifeedant from the Abundant Birchbark Triterpene Betulin. J. Agric. Food Chem. 38(2): 493-494. Cytotoxic 8.6 uM * Cytotoxic 600 ppm * Hypolipemic * Prostaglandin-Synthesis-Inhibitor IC50=119 uM Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626. Topoisomerase-II-Inhibitor IC50=38.6 uM *
22	BETULINIC-ACID	Seed	--	--	--	Pavannasasivam, G., & M.U.S. Sultanbawa. 1974. Betulinic acid in the Dilleniaceae and a review of its natural distribution. Phytochem. 13:2002-2006.
Anthelmintic * Antibacterial * Anticancer Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticarcinomic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiedemic * AntiHIV EC50=2.0 ug/ml Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095. AntiHIV IC50=6.5 ug/ml * AntiHIV 14.8 uM * Antiinflammatory Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas. Planta Medica, 61: 9. Antileukemic Antimalarial IC50=19-26 ug/ml * Antimelanomic New York Times, 3/28/95. Antinociceptive * Antiplasmodial IC50=19-26 ug/ml * Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiviral 14.8 uM * Apoptotic * Cytotoxic 16.4 uM * Cytotoxic 50-100 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al) Phospholipase-A2-Inhibitor * Prostaglandin-Synthesis-Inhibitor 200 ug/ml Dunstan, C. A., Liu, B., Welch, C. J., Perera, P., Bohlin, L. 1998. Alphitol, a Phenolic Substance from Alphitonia zizyphoides which Inhibits Prostaglandin Biosynthesis in vitro. Phytochemistry, 48(3): 495-497. Prostaglandin-Synthesis-Inhibitor IC50=101 uM Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
7	CEPHAELINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
Amebicide Merck 11th Edition Antimalarial IC50=0.011-0.027 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antiplasmodial IC50=0.011-0.027 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Emetic Martindale's 28th Expectorant Merck 11th Edition Pesticide * Protisticide *
0	DEOXYTUBULOSINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
1	ISOCEPHAELINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
HIF-1-Inhibitor IC50=1.1 muM *
0	ISOTUBULOSINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
0	NEOCEPHAELINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
0	PROTEMETINOL	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
0	PROTOEMETINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
2	PSYCHOTRINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
Antimalarial IC50=0.1-0.4 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antiplasmodial IC50=0.1-0.4 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3	SALSOLINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
Antihypertensive * Cardioactive 1-3 mg/kg * Hypotensive UNESCO. 1960. Medicinal Plants of the Arid Zones. eds.(botany) I.C. Chopra, B.K. Abrol and K.L. Hands; eds (pharmacology), R. Paris and G. Dillemann UNESCO, Place de Fontenoy, Paris 7E. 96 pp.
5	TUBULOSINE	Fruit	--	--	--	Itoh, A., Ikuta, Y., Tanahashi, T., Nagakura, N. 2000. Two Alangium Alkaloids from Alangium lamarckii. J. Natural Products, 63(5): 723-725.
Amebicide * Antimalarial IC50=0.006-0.011 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antiplasmodial IC50=0.006-0.011 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antitumor * Cytotoxic *

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Alangium lamarckii (Alangiaceae)

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