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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. URSOLIC-ACID

URSOLIC-ACID

Chemical ID
URSOLICACID
Ubiquitous
No

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Cardiotonic *
Choleretic 5-20 mg/kg orl Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
CNS-Depressant *
COX-2-Inhibitor IC50=130 uM/ *
Cyclooxygenase-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cytotoxic 7.2 uM *
Cytotoxic 50 ppm *
Cytotoxic ED50=3.75 ug/ml *
Diuretic *
Elastase-Inhibitor IC50=~15 uM *
Hepatoprotective 10 mg/kg *
Hepatoprotective 1-100 ug/ml *
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypotensive *
Immunomodulator *
Leucocytogenic *
Lipoxygenase-Inhibitor IC50=0.18 mM *
MMP-9-Inhibitor IC80=10 uM *
Ornithine-Decarboxylase-Inhibitor *
Pesticide *
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Crataegus laevigata Shoot *
Crataegus laevigata Leaf List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Crataegus monogyna Plant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Crataegus monogyna Inflorescence *
Crataegus rhipidophylla Leaf List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Crataegus rhipidophylla Shoot *
Cryptostegia grandifolia Leaf *
Duboisia myoporoides Shoot 10.0 -0.7 *
Duchesnea indica Plant 1.6 -0.8 *
Elaeagnus pungens Leaf Chemical Constituents of Oriental Herbs (3 diff. books)
Eriobotrya japonica Leaf 13.7 955.6 -0.4 *
Eucalyptus citriodora Plant J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
Eucalyptus citriodora Leaf *
Eucalyptus citriodora Root 67.0 1.0 *
Eucalyptus globulus Wood 8.0 *
Eucalyptus globulus Leaf Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Eucalyptus grandis Leaf 6000.0 -0.3 *
Forsythia suspensa Fruit *
Gaultheria fragrantissima Leaf =ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp
Gaultheria procumbens Leaf *