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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Chemical THYMOL

Chemical ID
THYMOL
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=1,800 (orl mus)
LD50=980 mg/kg (orl rat) Merck 11th Edition, Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Antimelanomic IC50=120 uM/l *
Antineuritic *
Antioxidant 100 ppm Martindale's 28th
Antioxidant (LDL) IC50=4 uM *
Antiperiodontic MIC=50-200 ug/ml *
Antiplaque MIC=39-625 ug/ml Osawa, K., Matsumoto, T., Maruyama, T., Takiguchi, T., Okuda, K., and Takazoe, I., Studies of the antibacterial activity of plant extracts and their constituents against periodontopathic bacteria, Bull Tokyo Dent. Coll., 31 (1), 1990, 17-21
Antiradicular EC=60 Jimenez, J., Navarro, M.C., Montilla, M.P., Martin, A. and Martinez, A. 1993. Thymus zygis Oil: Its Effects on CCl4-Induced Hepatotoxicity and Free Radical Scavenger Activity. JEO5: 153-8.
Antirheumatic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antisalmonella *
Antiseptic 20 x phenol Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antispasmodic *
Antistaphylococcic *
Antistreptococcic MIC=200-400 ug/ml *
Antitrichinosic 5% Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Antitussive Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Ataxigenic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Candidicide 100 ug/ml (>Nystatin) *
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Counterirritant Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Culicide LC50=36-49 mg/l *
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