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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. THEOPHYLLINE

THEOPHYLLINE

Chemical ID
THEOPHYLLINE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=600 (orl mus) CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
LDlo=100 (orl cat) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LDlo=350 (orl rbt) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LDlo=115 (ivn rbt) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LD50=200 (scu mus) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
ADI=60-200 orl/man/day Martindale's 28th
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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
(+)-Inotropic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Allergenic Martindale's 29th
Antiapneic Martindale's 29th
Antiasthmatic 5 mg/kg/orl/man Martindale's 29th
Antibradyarrhythmic Martindale's 29th
Antibronchitic *
Anticellulitic *
Antidote Charcoal & Propanolol Martindale's 29th
Antiemphysemic Martindale's 29th
Antineuralgic Martindale's 29th
Antirhinitic Martindale's 29th
Antispasmodic 100 uM *
Antiviral *
Arteriodilator *
Bronchodilator *
cAMP-Inhibitor IC50=0.06 mg/ml Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133.
cAMP-Phosphodiesterase-Inhibitor *
Cardiovascular 30 mg/kg orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
cGMP-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Camellia sinensis Leaf 2.0 4.0 -1.0 *
Camellia sinensis Seed *
Coffea arabica Leaf *
Coffea arabica Seed 5.0 -0.8 *
Ilex paraguariensis Leaf 0.0 500.0 1.0 *
Paullinia cupana Seed 0.0 2500.0 0.5 *
Theobroma angustifolium Seed 84.0 96.0 -0.8 *
Theobroma angustifolium Testa 113.0 116.0 -1.3 *
Theobroma angustifolium Petiole 47.0 52.0 -1.3 *
Theobroma bicolor Fruit 453.0 522.0 *
Theobroma bicolor Petiole 53.0 273.0 1.1 *
Theobroma bicolor Seed 196.0 216.0 -0.7 *
Theobroma bicolor Testa 210.0 211.0 0.3 *
Theobroma cacao Petiole 58.0 188.0 0.2 *
Theobroma cacao Plant *
Theobroma cacao Seed 0.0 4739.0 1.7 *
Theobroma cacao Testa 130.0 257.0 1.1 *