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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. NICOTINE

NICOTINE

Chemical ID
NICOTINE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=3-230 (orl mus) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006., Merck 11th Edition, Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD50=55 mg/kg (orl rat) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LDlo=1 mg/kg (orl hmn)
LDlo=30-60 mg/man Martindale's 28th
LD50=5 mg/kg (ivn dog)
LD50=7.1 mg/kg (ivn mus)
LD50=33.5 mg/kg (scu rat)
LD50=9.4 mg/kg (ivn rbt)
LD=6-9 mg/kg (ims cat) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=2 mg/kg (ivn cat) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=1 mg/kg (scu cat) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=9 mg/kg (ims cow) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=15 mg/kg (ims dog) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=15 mg/kg (ims gpg) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=30 mg/kg (ipr gpg) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=4.5 mg/kg (ivn gpg) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=80 mg/kg (scu gpg) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=8.8 mg/kg (ims horse) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=6 mg/kg (ims mky) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=8 mg/kg (ims mus) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=10 mg/kg (ipr mus) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=0.5 mg/kg (ivn mus) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=30 mg/kg (scu mus) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=14 mg/kg (ims pig) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=15 mg/kg (ims rat) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=20 mg/kg (ipr rat) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=3 mg/kg (ivn rat) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=190 mg/kg (orl rat)
LD=40 mg/kg (scu rat) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=30 mg/kg (ims rbt) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=14 mg/kg (ipr rbt) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=7 mg/kg (ivn rbt) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=200 mg/kg (orl rbt) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD=30 mg/kg (scu rbt) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Tranquilizer *
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Apium graveolens Plant Pakistan Encyclopedia Planta Medica. 1986.
Asclepias syriaca Sprout Seedling *
Atropa bella-donna Leaf *
Bacopa monnieri Plant Wealth of India.
Carica papaya Leaf 102.8 -0.7 Jim Duke's personal files.
Carica papaya Plant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Datura stramonium Plant *
Duboisia myoporoides Sprout Seedling *
Duboisia myoporoides Root *
Duboisia myoporoides Stem *
Duboisia myoporoides Leaf 1700.0 -0.7 *
Equisetum arvense Plant 0.4 *
Equisetum arvense Shoot Jim Duke's personal files.
Erythroxylum coca Leaf *
Huperzia spp Plant *
Juglans regia Leaf List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Lycopodium clavatum Pollen Or Spore Chemical Constituents of Oriental Herbs (3 diff. books)
Lycopodium lucidulum Plant *
Mucuna pruriens Seed *
Nicotiana glauca Leaf *