Chemical KAWAIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Dr. Duke's Phytochemical and Ethnobotanical Databases

U.S. Department of Agriculture

Chemical ID

KAWAIN

Ubiquitous

No

List of known dosages
Dosage	Reference
LD50=420 mg/kg (ipr mus)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=69 mg/kg (ivn mus)
LD50=1,130 mg/kg (orl mus)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Endoanesthetic	5-20 mg/kg	Duke, 1992 *
Fungicide	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
MAO-B-Inhibitor	not available	Duke, 1992 *
Myorelaxant	IC50 20 mg/kg ivn mus	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Myorelaxant	60 mg/kg ipr	Duke, 1992 *
Neurotoxic	not available	R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Pesticide	not available	Duke, 1992 *
Sedative	60 mg/kg ipr	Duke, 1992 *
Tranquilizer	not available	HerbalGram No. 24, page 37.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Piper methysticum	Resin, Exudate, Sap	not available	33800.0	not available	Duke, 1992 *
Piper methysticum	Leaf	not available	not available	not available	Duke, 1992 *
Piper methysticum	Rhizome	9300.0	12000.0	not available	Duke, 1992 *
Piper methysticum	Plant	not available	not available	not available	Duke, 1992 *
Piper methysticum	Root	not available	306.0	not available	Duke, 1992 *
Piper methysticum	Stem	not available	not available	not available	Duke, 1992 *