Chemical KAWAIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

KAWAIN

Ubiquitous

List of known dosages
Dosage	Reference
LD50=420 mg/kg (ipr mus)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=69 mg/kg (ivn mus)
LD50=1,130 mg/kg (orl mus)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Analgesic	300 mg/kg ipr mus	Duke, 1992 *
Anesthetic	=cocaine 0.25%	Duke, 1992 *
Antiaggregant	IC50=71-115 uM/l	Duke, 1992 *
Antiarachidonate	IC50=71-115 uM/l	Duke, 1992 *
Anticonvulsant	not available	Duke, 1992 *
Antidote (Strychnine)	(3 mg/kg) IC50=98 mg/kg	Duke, 1992 *
Antiedemic	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antifibrillary	20 mg/kg	Duke, 1992 *
Antiinflammatory	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimycotic	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antinociceptive	not available	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antiprostaglandin	not available	Duke, 1992 *
Antipyretic	not available	Duke, 1992 *
Antiseptic	not available	Duke, 1992 *
Antispasmodic	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antithrombotic	not available	Duke, 1992 *
Antithromboxane	IC50=71-115 uM/l	Duke, 1992 *
Anxiolytic	not available	Duke, 1992 *
CNS-Depressant	not available	Duke, 1992 *
Cyclooxygenase-Inhibitor	IC50=71-115 uM/l	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Piper methysticum	Leaf	not available	not available	not available	Duke, 1992 *
Piper methysticum	Rhizome	9300.0	12000.0	not available	Duke, 1992 *
Piper methysticum	Plant	not available	not available	not available	Duke, 1992 *
Piper methysticum	Root	not available	306.0	not available	Duke, 1992 *
Piper methysticum	Stem	not available	not available	not available	Duke, 1992 *
Piper methysticum	Resin, Exudate, Sap	not available	33800.0	not available	Duke, 1992 *