Chemical GOSSYPOL | Dr. Duke's Phytochemical and Ethnobotanical Databases

Dr. Duke's Phytochemical and Ethnobotanical Databases

U.S. Department of Agriculture

Chemical ID

GOSSYPOL

Ubiquitous

No

List of known dosages
Dosage	Reference
LD50=2,315-2,570 (orl rat)	Cooper-Driver, G. A., Chemical substances in plants toxic to animals, pp. 213-47 in Rechcigl, M., Jr., ed. CRC Handbook of Naturally Occurring Food Toxicants, CRC Press, Boca Raton, 1983, 339 pp.
LD50=550 (orl pig)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Interferonogenic	not available	Duke, 1992 *
Larvicide	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Libidolytic	not available	Martindale's 29th
Mutagenic	not available	Economic & Medicinal Plant Research, 6: 189.
Nematistat	125 ug/ml	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Paralytic	not available	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Pesticide	not available	Duke, 1992 *
Prostaglandigenic	not available	Economic & Medicinal Plant Research, 6: 189.
Prostaglandin-Synthesis-Inhibitor	8.4-380 nM	Xiao, D. M., Wang, X. L., Zhang, J. B., Chen, H. C. 1991. Effects of Gossypol of Phorbol Ester-Calcimycin-induced Prostaglandin Synthesis by Macrophages. Chin Med J, 104(4): 321-325.
Spermicide	0.2-100 uM	Duke, 1992 *
Spermicide	30 mg/kg rats	Duke, 1992 *
Topoisomerase-II-Inhibitor	3.4 uM	Duke, 1992 *
Toxic	not available	Economic & Medicinal Plant Research, 6: 189.
Tumorigenic	not available	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Abelmoschus esculentus	Seed	32.0	70.0	-0.5	Duke, 1992 *
Ceiba pentandra	Seed	not available	not available	not available	Duke, 1992 *
Glycine max	Seed	not available	60.0	-0.5	Duke, 1992 *
Gossypium sp	Oil	500.0	7000.0	not available	Duke, 1992 *
Gossypium sp	Seed	50.0	2500.0	-0.3	Duke, 1992 *
Helianthus annuus	Seed	not available	10.0	-0.6	Duke, 1992 *
Thespesia populnea	Root	not available	12500.0	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Thespesia populnea	Seed	not available	31400.0	2.0	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Thespesia populnea	Stem	not available	14300.0	not available	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Thespesia populnea	Flower	not available	4000.0	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Thespesia populnea	Leaf	not available	16600.0	not available	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.