Chemical (-)-EPICATECHIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

-EPICATECHIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Beta-Adrenergic Receptor Blocker	10 uM	Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447.
Cancer-Preventive	not available	Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic	not available	Duke, 1992 *
Choline-Sparing	not available	Duke, 1992 *
COMP-Inhibitor	not available	Dullo, A. G., et al. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am. J. Clinical Nutrition, 70: 1040-1045.
Cytotoxic	TC50=>100 ug/ml	Duke, 1992 *
Hypocholesterolemic	not available	Duke, 1992 *
Hypoglycemic	not available	Duke, 1992 *
Immunostimulant	not available	Duke, 1992 *
Insulinogenic	not available	Economic & Medicinal Plant Research, 6: 170.
Lipoxygenase-1-Inhibitor	IC50=60 mM	Duke, 1992 *
Lipoxygenase-Inhibitor	IC50=140 uM	Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Lipoxygenase-Inhibitor	IC97=5 mM	Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Pancreatogenic	not available	Duke, 1992 *
Pesticide	not available	Duke, 1992 *
Reverse-Transcriptase-Inhibitor	10 ng/ml	McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Vasodilator	uM	McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Xanthine-Oxidase-Inhibitor	IC50=>40	Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Abutilon theophrasti	Root	not available	not available	not available	Paszkowski, W. L., Kremer, R. J. 1988. Biological Activity and Tentative Identification of Flavonoid Components in Velvetleaf (Abutilon theophrasti Medik.) Seed Coats. J. Chem. Ecol., 14(7): 1573-1582.
Aesculus hippocastanum	Seed Coat	816.3	4000.0	not available	Jim Duke's personal files.
Aesculus hippocastanum	Bark	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Aesculus hippocastanum	Fruit Epidermis	not available	not available	not available	Jim Duke's personal files.
Aesculus hippocastanum	Leaf	not available	not available	not available	Jim Duke's personal files.
Arctostaphylos uva-ursi	Leaf	not available	not available	not available	Duke, 1992 *
Camellia sinensis	Flower	not available	not available	not available	Duke, 1992 *
Camellia sinensis	Stem	0.1	not available	not available	Duke, 1992 *
Camellia sinensis	Leaf	960.0	32500.0	1.4	Duke, 1992 *
Camellia sinensis	Tissue Culture	not available	not available	not available	Duke, 1992 *
Ceratonia siliqua	Fruit	not available	not available	not available	Wealth of India.
Cinchona pubescens	Bark	not available	not available	not available	Duke, 1992 *
Cinchona spp	Bark	not available	not available	not available	Chemical Constituents of Oriental Herbs (3 diff. books)
Cinnamomum aromaticum	Bark	not available	not available	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Cinnamomum sieboldii	Plant	not available	not available	not available	Duke, 1992 *
Cinnamomum verum	Bark	not available	11.0	-1.0	Duke, 1992 *
Crataegus laevigata	Fruit	not available	not available	not available	Duke, 1992 *
Crataegus laevigata	Flower	not available	not available	not available	Duke, 1992 *
Crataegus laevigata	Leaf	not available	not available	not available	Duke, 1992 *
Crataegus laevigata	Shoot	not available	not available	not available	Duke, 1992 *