Chemical EMODIN

List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)

Activity Sort descending	Dosage	Reference
MMP-7-Inhibitor	not available	Duke, 1992 *
MMP-9-Inhibitor	not available	Duke, 1992 *
Mutagenic	not available	Duke, 1992 *
NO-Inhibitor	IC50=60.7 uM	Duke, 1992 *
Pesticide	not available	Duke, 1992 *
PGE2-Inhibitor	not available	Duke, 1992 *
Prostaglandin-Synthesis-Inhibitor	IC50=23 uM/ml	Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414.
Protein-Kinase-C-Inhibitor	IC50=25 uM	Duke, 1992 *
PTK-Inhibitor	IC50=19-37 uM	Duke, 1992 *
PTK-Inhibitor	10-100 uM	Duke, 1992 *
Purgative	ED50=>500 mg/kg orl mus	Duke, 1992 *
Styptic	not available	Duke, 1992 *
Topoisomerase-II-Inhibitor	1 mM	Muller, S. O., Eckert, I., Lutz, W. K., Stopper, H. 1996. Genotoxicity of the Laxative Drug Components Emodin, Aloe-emodin and Danthron in Mammalian Cells: Topoisomerase II Mediated? Mutat Res, 371: 165-173.
Topoisomerase-II-Inhibitor	IC50=7 uM/ml	Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414.
Trichomonicide	not available	Duke, 1992 *
Tyrosine-Kinase-Inhibitor	not available	Duke, 1992 *
Vasodilator	not available	Duke, 1992 *
Vasorelaxant	not available	Duke, 1992 *