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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. BERBERINE

BERBERINE

Chemical ID
BERBERINE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=100 mg/kg
LD50=24 mg/kg (ipr mus)
LD50=329 (orl mus)
LD50=10-20 (ivn dog)
LD50=27.5 mg/kg man
LD50=>1,000 mg/kg (orl rat)
LD50=8.2 mg/kg (ivn mus) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD50=26.4 mg/kg (ipr mus) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD50=13.2 mg/kg (scu mus) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Antiherpetic *
Antihistaminic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiinflammatory *
Antiischemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Antileishmanic 10 ug/ml *
Antilipogenic IC63=10 uM Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Antimalarial 0.14-0.36 ug/ml *
Antimalarial 50 uM *
Antimitotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Antimuscarinic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antimyalgic *
Antimycotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Antineoplastic *
Antinephritic *
Antiperistaltic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Antipharyngitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiphotooxidative *
Antiplasmodial IC50=0.14-0.36 ug/ml *
Antipneumonic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antipyretic 3 x aspirin *
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Adonis vernalis Plant *
Andira inermis Bark *
Argemone mexicana Plant 410.0 *
Berberis vulgaris Plant Jim Duke's personal files.
Berberis vulgaris Root 4000.0 64800.0 1.1 *
Berberis vulgaris Bark 45000.0 1.0 Jim Duke's personal files.
Berberis vulgaris Root Bark 25000.0 80000.0 *
Berberis vulgaris Stem Bark 20000.0 25000.0 1.0 Jim Duke's personal files.
Berberis vulgaris Flower 6600.0 Jim Duke's personal files.
Berberis vulgaris Stem 1600.0 28900.0 Jim Duke's personal files.
Berberis vulgaris Leaf 3000.0 1.0 Jim Duke's personal files.
Caulophyllum thalictroides Plant Jim Duke's personal files.
Chelidonium majus Plant *
Coptis chinensis Rhizome 40000.0 90000.0 0.9 *
Coptis japonica Rhizome 40000.0 70000.0 -0.3 *
Coptis spp Rhizome 40000.0 90000.0 0.9 *
Corydalis spp Plant *
Eschscholzia californica Shoot List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Hydrastis canadensis Plant *
Hydrastis canadensis Rhizome 50000.0 -1.5 *