Chemical BERBERINE | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

BERBERINE

Ubiquitous

List of known dosages
Dosage	Reference
LD50=100 mg/kg
LD50=24 mg/kg (ipr mus)
LD50=329 (orl mus)
LD50=10-20 (ivn dog)
LD50=27.5 mg/kg man
LD50=>1,000 mg/kg (orl rat)
LD50=8.2 mg/kg (ivn mus)	Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD50=26.4 mg/kg (ipr mus)	Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD50=13.2 mg/kg (scu mus)	Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Sort descending	Dosage	Reference
Antiherpetic	not available	Duke, 1992 *
Antihistaminic	not available	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiinflammatory	not available	Duke, 1992 *
Antiischemic	not available	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antileishmanic	10 ug/ml	Duke, 1992 *
Antilipogenic	IC63=10 uM	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antimalarial	50 uM	Duke, 1992 *
Antimalarial	0.14-0.36 ug/ml	Duke, 1992 *
Antimitotic	not available	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antimuscarinic	not available	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antimyalgic	not available	Duke, 1992 *
Antimycotic	not available	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antineoplastic	not available	Duke, 1992 *
Antinephritic	not available	Duke, 1992 *
Antiperistaltic	not available	Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Antipharyngitic	not available	Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiphotooxidative	not available	Duke, 1992 *
Antiplasmodial	IC50=0.14-0.36 ug/ml	Duke, 1992 *
Antipneumonic	not available	Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antipyretic	3 x aspirin	Duke, 1992 *

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