Chemical ATROPINE | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

ATROPINE

Ubiquitous

List of known dosages
Dosage	Reference
LD50=400 mg/kg (orl mus)
LD50=622-750 mg/kg (orl rat)	Merck 11th Edition, Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
LD50=700 (orl)
LDlo=100 mg/man	Martindale's 29th, Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
LD50=1,100 mg/kg (orl gpg)
LDlo=1,450 mg/kg (orl dog)	Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
LD50=100 (orl hmn)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=129 mg/kg (ipr mus)	Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
MLD=1,450 mg/kg (orl rbt)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Allergenic	not available	Duke, 1992 *
Analgesic	not available	Duke, 1992 *
Anesthetic	not available	Martindale's 29th
Anhydrotic	not available	Duke, 1992 *
Antianoxic	not available	Martindale's 29th
Antiarrhythmic	400-1,000 ug	Duke, 1992 *
Antiasthmatic	not available	Martindale's 28th
Antibradycardic	300-600 ug/ims/man/day	Martindale's 28th
Anticholinergic	0.55 mg/kg orl mus	Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Anticholinergic	10 mg/kg orl rat	Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antidote (Anticholinesterase)	2 mg/man/ims	Martindale's 29th
Antidote (Black Widow)	not available	Martindale's 29th
Antidote (Lobelia)	2 mg scu	Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antidote (Muscarine)	not available	Duke, 1992 *
Antidote (Mushroom)	not available	Martindale's 30th
Antidote (Organophosphorus)	2-10 mg/ims/man	Martindale's 29th
Antidote (Poison Gas)	not available	Duke, 1992 *
Antidote (Tetrodotoxin)	not available	Duke, 1992 *
Antiemetic	not available	Martindale's 29th
Antiemphysemic	not available	Martindale's 29th

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Anisodus tanguticus	Plant	not available	not available	not available	Duke, 1992 *
Arctium lappa	Root	0.3	30.0	1.0	Jim Duke's personal files.
Atropa bella-donna	Root	not available	not available	not available	Duke, 1992 *
Brugmansia amesianum	Plant	not available	not available	not available	Duke, 1992 *
Datura candida	Root	not available	not available	not available	Duke, 1992 *
Datura innoxia	Plant	not available	not available	not available	Duke, 1992 *
Datura metel	Seed	not available	not available	not available	Duke, 1992 *
Datura stramonium	Plant	800.0	1000.0	not available	Duke, 1992 *
Duboisia myoporoides	Stem	not available	0.0	-1.0	Duke, 1992 *
Duboisia myoporoides	Root	not available	not available	not available	Duke, 1992 *
Duboisia myoporoides	Leaf	not available	0.0	-1.0	Duke, 1992 *
Hyoscyamus niger	Leaf	not available	not available	not available	Duke, 1992 *
Hyoscyamus niger	Seed	not available	not available	not available	Duke, 1992 *
Latua pubiflora	Leaf	490.0	1590.0	1.0	Duke, 1992 *
Latua pubiflora	Seed	not available	685.0	not available	Duke, 1992 *
Latua pubiflora	Stem	2085.0	4600.0	1.0	Duke, 1992 *
Mandragora officinarum	Root	10.0	20.0	-1.0	Duke, 1992 *
Scopolia carniolica	Rhizome	not available	300.0	not available	Duke, 1992 *
Solanum dulcamara	Seed	not available	not available	not available	Duke, 1992 *