Chemical ATROPINE | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

ATROPINE

Ubiquitous

List of known dosages
Dosage	Reference
LD50=400 mg/kg (orl mus)
LD50=622-750 mg/kg (orl rat)	Merck 11th Edition, Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
LD50=700 (orl)
LDlo=100 mg/man	Martindale's 29th, Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
LD50=1,100 mg/kg (orl gpg)
LDlo=1,450 mg/kg (orl dog)	Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
LD50=100 (orl hmn)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=129 mg/kg (ipr mus)	Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
MLD=1,450 mg/kg (orl rbt)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Sort descending	Dosage	Reference
Allergenic	not available	Duke, 1992 *
Analgesic	not available	Duke, 1992 *
Anesthetic	not available	Martindale's 29th
Anhydrotic	not available	Duke, 1992 *
Antianoxic	not available	Martindale's 29th
Antiarrhythmic	400-1,000 ug	Duke, 1992 *
Antiasthmatic	not available	Martindale's 28th
Antibradycardic	300-600 ug/ims/man/day	Martindale's 28th
Anticholinergic	0.55 mg/kg orl mus	Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Anticholinergic	10 mg/kg orl rat	Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antidote (Anticholinesterase)	2 mg/man/ims	Martindale's 29th
Antidote (Black Widow)	not available	Martindale's 29th
Antidote (Lobelia)	2 mg scu	Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antidote (Muscarine)	not available	Duke, 1992 *
Antidote (Mushroom)	not available	Martindale's 30th
Antidote (Organophosphorus)	2-10 mg/ims/man	Martindale's 29th
Antidote (Poison Gas)	not available	Duke, 1992 *
Antidote (Tetrodotoxin)	not available	Duke, 1992 *
Antiemetic	not available	Martindale's 29th
Antiemphysemic	not available	Martindale's 29th

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