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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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  2. APIGENIN

APIGENIN

Chemical ID
APIGENIN
Ubiquitous
No

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Ornithine-Decarboxylase-Inhibitor *
P21-Inducer 10-70 uM *
Pesticide *
PKC-Inhibitor IC50=10 uM *
Polyamine-Synthesis-Inhibitor *
Progestational *
Protein-Kinase-C-Inhibitor IC50=10-40 uM *
PTK-Inhibitor 10-100 uM *
Quinone-Reductase-Inducer 20 uM Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Radioprotective *
Sedative 30-100 mg/kg *
Sunscreen *
TNF-alpha-Inhibitor IC50=3.27 uM *
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor IC28=18 uM *
Topoisomerase-II-Inhibitor IC45=180 uM *
Topoisomerase-II-Inhibitor 50 ug/ml Azuma, Y., Onishi, Y., Sato, Y., Kizaki, H. 1995. Effects of Protein Tyrosine Kinase Inhibitors With Different Modes of Action on Topoisomerase Activity and Death of IL-2-Dependent CTLL-2-Cells. J Biochemistry, 118: 312-318.
Uterotrophic EC50=0.1-25 uM/l Journal of Medicinal Food 2: 227.1999.
Vasodilator *
VEGF-Inhibitor IC50=2-7 uM *
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Trigonella foenum-graecum Plant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Triticum aestivum Seed *