EUGENOL-ACETATE |
1 mM rbt |
Chen, S. J., Wang, M. H., Chen, I. J. 1996. Antiplatelet and Calcium Inhibitory Properties of Eugenol and Sodium Eugenol Acetate. Gen Pharmacol, 27(4): 629-633. |
FALCARINOL |
not available |
Fujimoto, Y., et al. 1998. Inhibition of 15-hydroxyprostaglandin Dehydrogenase Activity in Rabbit Gastric Antral Mucosa by Panaxynol Isolated from Oriental Medicines. J Pharmacy & Pharmacology, 50(9): 1075-1078. |
FERULIC-ACID |
0.58-3.2 mM |
Xu, L. N., Yu, W. G., Tian, J. Y., Liu, Q. Y. 1990. Effect of Sodium Ferulate on Arachidonic Acid Metabolism. Yao Hsueh Hsueh Pao, 25(6): 412-416. |
GALLIC-ACID-PROPYL-ESTER |
IC50=100 uM |
Alanko, J., et al. 1999. Modulation of Arachidonic Acid Metabolism by Phenols: Relation to their Structure and Antioxidant/Proooxidant Properties. Free Radical Biol Med, 26(1/2): 193-201. |
GINSENOSIDE-RC |
500 ug/ml |
Park, C. W. 1992. The Effects of Ginseng Components on Arachidonic Acid Metabolism. Korean J Ginseng Science, 16(1): 69-71. |
GLAUCOCALYXIN-A |
10 uM rbt |
Zhang, B., Long, K., Jiang, Y. Y. 1992. Effects of Glaucocalyxin a on PAF Biosynthesis and Arachidonic Acid Metabolism in Washed Rabbit Platelets. Zhongguo Yaolixue ye Dulixue Zazhi, 6(1): 52-55. |
GLYCYRRHIZIN |
100 mg/kg igs mus |
Ren, J., Cheng, J. X., Wang, Z. G. 1988. Effects of Ammonium Glycyrrhizinate on the Synthesis of Prostaglandins E2 and F2-alpha. K'o Hsueh T'ung Pao, (3): 227-229. |
GOSSYPOL |
8.4-380 nM |
Xiao, D. M., Wang, X. L., Zhang, J. B., Chen, H. C. 1991. Effects of Gossypol of Phorbol Ester-Calcimycin-induced Prostaglandin Synthesis by Macrophages. Chin Med J, 104(4): 321-325. |
GUAIACOL |
IC50=57 uM |
Alanko, J., et al. 1999. Modulation of Arachidonic Acid Metabolism by Phenols: Relation to their Structure and Antioxidant/Proooxidant Properties. Free Radical Biol Med, 26(1/2): 193-201. |
LABDA-TRANS-8(17)-12-DIENE-15-16-DIAL |
IC50=100 uM |
Kawakishi, S., Morimitsu, Y., Osawa, T. 1994. Chemistry of Ginger Components and Inhibitory Factors of the Arachidonic Acid Cascade. ASC Symp Ser, 547: 244-250. |
MYRICETIN-3-O-BETA-D-GLUCURONIDE |
1 ug rbt |
Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427. |
NORATHYRIOL |
IC50=29.1 mg/kg ipr mus |
Wang, J. P., Ho, T. F., Lin, C. N., Tang, C. M. 1994. Effect of Norathryiol, Isolated from Tripterospermum lanceolatum, on A23 187-Induced Pleurisy and Analgesia in Mice. Naunyn-Schmiedeberg's Arch Pharmacol, 350(1): 90-95. |
OLEANOLIC-ACID |
igs mus |
Duke, 1992 * |
P-COUMARIC-ACID |
not available |
Duke, 1992 * |
PYROGALLOL |
IC50=900 uM |
Alanko, J., et al. 1999. Modulation of Arachidonic Acid Metabolism by Phenols: Relation to their Structure and Antioxidant/Proooxidant Properties. Free Radical Biol Med, 26(1/2): 193-201. |
QUERCETIN |
40 ug/ml |
Ibewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284. |
SALIPURPOSIDE |
IC50=13.14 uM |
Ogundaini, A., Farah, M., Perera, P., Samuelsson, G., Bohlin, L. 1996. Isolation of two new Antiinflammatory Biflavanoids from Sarcophyte piriei. J Natural Products, 59(6): 587-590. |
SHIKONOFURAN-B |
20 ug/ml (72% inhibition) |
Yao, X. S., et al. 1991. Biologically Active Constituents of Arnebia euchroma: Structure of Arnebinol, an Ansa-Type Monoterpenylbenzenoid with Inhibitory Activity on Prostaglandin Biosynthesis. Chem & Pharm Bull, 39(11): 2956-2961. |
SHIKONOFURAN-C |
20 ug/ml (72% inhibition) |
Yao, X. S., et al. 1991. Biologically Active Constituents of Arnebia euchroma: Structure of Arnebinol, an Ansa-Type Monoterpenylbenzenoid with Inhibitory Activity on Prostaglandin Biosynthesis. Chem & Pharm Bull, 39(11): 2956-2961. |
SINOMENINE |
IC50=1 mM |
Liu, L, Riese, J., Resch, K., Kaever, V. 1994. Impairment of Macrophage Eicosanoid and Nitric Oxide Production by an Alkaloid from Sinomenium acutum. Arzneim-Forsch, 44(11): 1223-1226. |