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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Cytotoxic

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
MIKANOLIDE <1 ppm *
MITROXANTHONE IC50=0.02-1.54 ug/ml Hou, A., Li, M, Jiang, B., Lin, Z., Ji, S., Zhou, Y., Sun, H. 2000. New 7,20:14,20-Diepoxy ent-Kauranoids from Isodon xerophilus. J. Natural Products, 63(5): 599-601.
MOLEPHANTIN ED50=0.33 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
MOLEPHANTININ ED50=2.5 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
MONTANIN ED50=0.06 *
MULTIRADIATIN 20-120 ppb Biosyn. Prod. Cancer Chemotherapy (Petit et al)
N,N-BISNORAROMOLINE ED50=3.9 Collins, D.J., Culvenor, C.C.J., Lamberton, J.A., Loder, J.W. and Price, J.R., Plants for Medicines, CSIRO, East Melbourne, Australia, 1990, 303 pp.
N-(3,4,5-TRIMETHOXYCINNAMOYL)-DELTA-3-PYRIDIN-2-ONE ED50=0.45-1.8ug/ml PM56(6):52 *
N-(3,4-DIMETHOXYCINNAMOYL)-DELTA-3-PYRIDIN-2-ONE 0.86-3.23 ug/ml *
N-(3-METHOXY-4,5-METHYLENEDIOXYCINNAMOYL)-DELTA-3-PYRIDIN-2-ONE ED50=0.4-2.6ug/ml *
N-(3-METHOXY-4,5-METHYLENEDIOXYDIHYDROCINNAMOYL)-DELTA-3-PYRIDIN-2-ONE ED50=2-5ug/ml *
NEOJUSTICIN-B 4 ppm *
NERIIFOLIN 9KB ED50=0.022 ppm Alkofahi, A., Rupprect, J. K., Anderson, J. E., McLaughlin, J. L., Mikolajczak, K. L., and Scott, B. A., Search for new pesticides from higer plants, Chap. 3 in ???, Arnason et al, eds, ACS, Washington, 1989
NIMBININ ED50=7.13 ug/mL *
NIMBOLIDE ED50=10.14 ug/mL *
NIVEUSIN Rizk, A.F.M. and Al-Nowaihi, A.S., The Phytochemistry of the Horticultural Plants of Qatar, Scientific and Applied Research Centre, University of Qatar.
NIVEUSIN-C Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NORCASSAIDIDE ED50=18 ppm *
NORCASSAMIDINE *
NORDIHYDROGUAIARETIC-ACID *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Rotala floribunda 1 0
Roylea elegans 1 0
Rubus fruticosus Blackberry 2 0
Rubus idaeus Red Raspberry; Raspberry 8 100
Rubus parviflorus Salmonberry; Thimbleberry 1 0
Rubus spectabilis Salmonberry 1 0
Rumex acetosa Garden Sorrel 2 0
Rumex acetosella Sheep Sorrel 1 0
Rumex crispus Curly Dock; Lengua De Vaca; Yellow Dock; Sour Dock 4 10, 408
Ruta graveolens Rue 5 0
Rzedowskia tolantonguensis 1 0
Salacia cordata 1 5.400000095367432
Salix alba White Willow 4 0
Salvia beckeri 1 0
Salvia farinacea 1 0
Salvia longistyla 1 56.400001525878906
Salvia mexicana 1 0
Salvia nicolsoniana 1 117.4000015258789
Salvia officinalis Sage 14 172, 930
Salvia sclarea Clary Sage 3 34, 920