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Biological Activity COX-1-Inhibitor

List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=10 uM/ Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
N-2'-METHYL-BUTYL-DECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-DODECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-HEXADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-TETRADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PELLITORINE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PINOSTROBIN IC36=100 ug/ml Duke, 1992 *
PTEROSTILBENE IC50=20 uM Duke, 1992 *
PUNICIC-ACID not available Duke, 1992 *
RESVERATROL ED50=15 uM Duke, 1992 *
RESVERATROL 50 uM/ Jang, M. S., Pezzuto, J. M. 1998. Resveratrol Blocks Eicosanoid Production and Chemically-Induced Cellular Transformation: Implication for Cancer Chemoprevention. Pharm Biol Suppl, 36: 28-34.
ROSMARINIC-ACID IC58=1,000 uM Duke, 1992 *
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Marrubium vulgare Horehound; White Horehound 1 0
Matricaria recutita Annual Camomile; German Camomile; Wild Camomile 1 25, 200
Medicago sativa Alfalfa; Lucerne 4 1, 226
Melaleuca bracteata Bracteate Tea-Tree 1 0
Melaleuca viridiflora Broad-Leaf Tea-Tree; Niaouli 1 0
Melia azedarach Chinaberry 2 0
Melicoccus bijugatas Genip; Honey berry; Mamoncillo; Pitomba 1 56
Melissa officinalis Balm; Lemonbalm; Melissa; Bee Balm 2 188, 000
Mentha aquatica Water Mint 2 27, 000
Mentha arvensis var. piperascens Cornmint; Field Mint; Japanese Mint 2 84, 684
Mentha longifolia Biblical Mint 2 29, 000
Mentha pulegium European Pennyroyal 3 76, 320
Mentha spicata Spearmint; Hortela da Folha Miuda 4 196, 750
Mentha x piperita Peppermint 3 32, 038
Mentha x rotundifolia Applemint 2 35, 600
Menyanthes trifoliata Bogbean; Buckbean; Bog Myrtle; Marsh Clover; Marsh Trefoil; Water Trefoil 1 0
Micromeria congesta Kaya Yarpuzu 1 15
Micromeria fruticosa Tea Hyssop; Zopha; Zuta 1 0
Micromeria myrtifolia Dagcayi; Haydarotu; Topukcayi 1 0
Mimosa pudica Sensitive Plant 1 930