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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
CHRYSOSPLENETIN IC50=23 uM *
CHRYSOSPLENOL-D IC50=32 uM *
CINCHONIDINE 150-500 mg/man/4 x day *
CINCHONINE LD50=152 (ipr rat) Merck 11th Edition
CIRSILINEOL IC50=36 uM *
CLAUSARIN IC50=0.1-0.7 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
COCSULINE IC50=15.56 ug/mL *
COLCHICINE 500 ug/10x/day/man Martindale's 28th
COLUMBAMINE 0.72 ug/ml *
CONOPHARYNGINE IC50=0.24-0.29 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CORONARIDINE IC50=1.3-2.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CORYNANTHEDINE IC50=41 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CORYNANTHEINE IC50=81 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CORYNANTHINE IC50=>200 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
COSTARICINE IC50=0.1-0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
COWAXANTHONE IC50=1.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CROSTPARINE IC50=2.1-3.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CRYPTOHEPINE IC50=0.8-1.2 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CRYPTOLEPINE IC50=0.031 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CRYPTOLEPINE IC50=0.1-0.2 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Diospyros discolour 1 1, 300
Diospyros ebenum 1 80
Diospyros eriantha 1 0
Diospyros ferrea 1 0
Diospyros fragrans 1 0
Diospyros gabunensis 1 0
Diospyros gracilescens 1 60
Diospyros greenwayi 1 60
Diospyros hirsuta 1 700
Diospyros hoyleana 1 410
Diospyros ismailii 1 0
Diospyros iturensis 1 660
Diospyros japonica 1 0
Diospyros kaki Persimmon 1 0
Diospyros kamerunensis 1 0
Diospyros leucomelas 1 0
Diospyros longiflora 1 393
Diospyros lotus 1 20
Diospyros mafiensis 1 200
Diospyros maingayi 1 0