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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
SECURININE 5.4 ug/ml *
SERGEOLIDE ED50=0.26 mg/kg day Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
SIMALIKALACTONE-D IC50=0.001-0.002 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SIPANDINOLIDE IC50=46 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SKIMMIANINE IC50=48.2 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
SUNGUCINE IC50=7.8-10.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SWERCHIN Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
TALCARPINE IC50=40.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TERMILIGNAN IC50=6-9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
THALIFABERIDINE IC50=0.12-0.88 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
THALIFABERINE IC50=0.44-5.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
THALIFASINE IC50=0.05-0.24 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TILIACORINE IC50=0.67 ug/ml *
TILIACORININE IC50=3.5 ug/ml *
TOMENTOSRIN IC50=7.8 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TOTAQUINE 600 mg/3x/day/man Martindale's 29th
TRANS-PINOCARVEOL IC50=5-50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TRANS-PINOCARVYL-HYDROPEROXIDE IC50=7.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TRICHIRUBRINE-A IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TRIGILLETIMINE IC50=22 ug/ml (ca 1/200 x chloroquine) *
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Eucalyptus fasiculosa 5 22.199999809265137
Eucalyptus forrestiana 3 420
Eucalyptus globulus Blue Gum; Eucalypt; Tasmanian Bluegum 8 82, 225.20000004023
Eucalyptus grandis Gum; Flooded Gum; Rose Gum 1 18, 000
Eucalyptus incrassata 3 580
Eucalyptus intertexta 5 156.5
Eucalyptus lansdowneana 5 19.800000190734863
Eucalyptus largisparsa 5 151.19999980926514
Eucalyptus leucoxylon 5 241
Eucalyptus macrorrhuncha 1 200, 000
Eucalyptus maculata Gum 2 85.10000000149012
Eucalyptus maideni 2 185.10000000149012
Eucalyptus melanophloia 5 11.600000023841858
Eucalyptus melliodora 2 185.10000000149012
Eucalyptus moluccana 2 240.10000000149012
Eucalyptus nova-anglica New England 'peppermint' 2 180
Eucalyptus occidentalis 2 75.10000000149012
Eucalyptus ochrophloia 4 11
Eucalyptus odorata 5 334.40000009536743
Eucalyptus oviformis 2 0.20000000298023224