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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
NARDISINONE IC50=1.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NARDOPEROXIDE IC50=1.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NB-METHYLAFFINISINE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-A IC50=0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-B IC50=0.6 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-C/D IC50=0.6 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMBANDIOL IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMBIN IC50=50 ug/ml *
NIMBININ IC50=0.77 ug/ml *
NIMBOLIDE IC50=0.001 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMBOLIDE IC50=1.74 ug/mL *
NIMOCINOL IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NOR-TILIACORINE-A IC50=0.56 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NORFLUOROCURARINE IC50=129 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NORTILIACORININE-A *
NYASOL IC50=12 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
O-METHYLEXOSTEMIN IC50=1.6-3.6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
O-METHYLMACRALSTONINE IC50=0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OBAMEGINE IC50=0.51 ug/ml (1/4 x chloroquine) *
OLEANOLIC-ACID IC50=70-89 ug/ml *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Coriandrum sativum Coriander; Chinese Parsley; Cilantro 3 4, 800
Coriaria myrtifolia Mealy Tree 2 0
Coriaria thymifolia Ground Toot; Shanshi 2 0
Cornus capitata 1 163.3000030517578
Cornus florida American Dogwood 3 40, 000
Cornus mas Cornelian Cherry; Sorbet 4 0
Cornus officinalis Chinese Dogwood 2 0
Corydalis spp Fumewort 2 0
Corylus avellana English Filbert; European Filbert; European Hazel; Hazel; Cobnut 1 0
Cotylelobium scabriusculum 1 170
Crataegus cuneata Hawthorn 2 0
Crataegus laevigata Hawthorn; English Hawthorn; Whitethorn; Woodland Hawthorn 5 0
Crataegus monogyna Hawthorn; English Hawthorn 4 40
Crataegus pentagyna Hawthorn 1 0
Crataegus rhipidophylla Hawthorn 4 0
Crateva religiosa 1 0
Crocus sativus Saffron 2 0
Crotalaria semperflorens 1 0
Cryptostegia grandifolia Rubber Vine 1 0
Cucumis melo Cantaloupe; Melon; Muskmelon; Netted Melon; Persian Melon; Nutmeg Melon 3 0