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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Biological Activity Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(+)-1,2-DEHYDROTELOBINE IC50=0.26-0.31 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-N-METHYLTELOBINE IC50=0.09-0.26 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-CEPHARANTHINE IC50=0.05-0.13 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-ISOTETRANDRINE IC50=0.05-0.07 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-OBABERINE IC50=0.05-0.09 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-THALRUGOSINE IC50=0.07-0.13 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-AROMOLINE IC50=0.67 ug/ml (ca 1/5 chloroquine) *
(+)-CEPHARANTHINE IC50=0.14-0.30 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-CRINAMINE IC50=2.8-3.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-DEPHNANDRINE IC50=0.06-0.22 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-HOMOAROMOLINE IC50=0.02-0.29 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-ISOTETRANDRINE IC50=0.05-0.17 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-OBABERINE IC50=0.22-0.23 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-STEPHIBABERINE IC50=0.13-0.31 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-TETRANDRINE IC50=0.16-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-THALRUGOSINE IC50=0.06-0.23 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ANONAINE IC50=1290-1900 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ASIMILOBINE IC50=470-950 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CAPAURINE IC50=1910-4340 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CASSYTHICINE IC50=2260-2290 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Coriandrum sativum Coriander; Chinese Parsley; Cilantro 3 4, 800
Coriaria myrtifolia Mealy Tree 2 0
Coriaria thymifolia Ground Toot; Shanshi 2 0
Cornus capitata 1 163.3000030517578
Cornus florida American Dogwood 3 40, 000
Cornus mas Cornelian Cherry; Sorbet 4 0
Cornus officinalis Chinese Dogwood 2 0
Corydalis spp Fumewort 2 0
Corylus avellana English Filbert; European Filbert; European Hazel; Hazel; Cobnut 1 0
Cotylelobium scabriusculum 1 170
Crataegus cuneata Hawthorn 2 0
Crataegus laevigata Hawthorn; English Hawthorn; Whitethorn; Woodland Hawthorn 5 0
Crataegus monogyna Hawthorn; English Hawthorn 4 40
Crataegus pentagyna Hawthorn 1 0
Crataegus rhipidophylla Hawthorn 4 0
Crateva religiosa 1 0
Crocus sativus Saffron 2 0
Crotalaria semperflorens 1 0
Cryptostegia grandifolia Rubber Vine 1 0
Cucumis melo Cantaloupe; Melon; Muskmelon; Netted Melon; Persian Melon; Nutmeg Melon 3 0