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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
NARDISINONE IC50=1.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NARDOPEROXIDE IC50=1.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NB-METHYLAFFINISINE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-A IC50=0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-B IC50=0.6 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-C/D IC50=0.6 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMBANDIOL IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMBIN IC50=50 ug/ml *
NIMBININ IC50=0.77 ug/ml *
NIMBOLIDE IC50=0.001 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMBOLIDE IC50=1.74 ug/mL *
NIMOCINOL IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NOR-TILIACORINE-A IC50=0.56 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NORFLUOROCURARINE IC50=129 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NORTILIACORININE-A *
NYASOL IC50=12 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
O-METHYLEXOSTEMIN IC50=1.6-3.6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
O-METHYLMACRALSTONINE IC50=0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OBAMEGINE IC50=0.51 ug/ml (1/4 x chloroquine) *
OLEANOLIC-ACID IC50=70-89 ug/ml *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Caulophyllum thalictroides Blue Cohosh 1 0
Ceanothus americanus 1 7, 479
Ceanothus velutinus 1 0
Cedrus deodora Deodar Cedar 1 0
Ceiba pentandra Kapok; Silk-Cotton Tree 3 0
Centaurea calcitrapa Star-Thistle 2 0
Centaurea cyanus Cornflower; Bachelor's Button 1 0
Centaurium erythraea Centaury 2 0
Centella asiatica Gotu Kola; Pennywort 2 2, 200
Cephaelis ipecacuanha Ipecac; Raicilla 3 96, 900
Cephalotaxus drupacea Plum Yew 1 0
Cephalotaxus fortunei Fortune's Plum Yew 1 0
Cephalotaxus harringtonii Japanese Plum Yew 1 1.2000000476837158
Cephalotaxus spp Generic Plum Yew 1 0
Ceratonia siliqua Carob; St.John's-Bread; Locust Bean 1 0
Chamaecrista greggii 1 14.800000190734863
Chamaemelum nobile Garden Camomile; Perennial Camomile; Roman Camomile 5 0
Chelidonium majus Celandine 1 0
Chenopodium album Lambsquarter 2 0
Chenopodium ambrosioides Epazote; Wormseed 1 36, 000