Plant Holarrhena pubescens (Apocynaceae) | Dr. Duke's Phytochemical and Ethnobotanical Databases

Common Names

Tellicherry Bark; Zhi Xie Mu; Conessi; Kurchi

How this plant is used

Medicinal

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List of plant chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Activity Count	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
DIHYDROISOCONESSIMINE	0	Bark	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
DIHYDROISOCONESSIMINE	0	Stem Bark	not available	not available	not available	Duke, 1992 *
DIHYDROISOCONESSINE	0	Bark	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
ERGOSTENOL	0	Bark	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
FAT	0	Seed	190000.0	300000.0	0.18	Duke, 1992 *
GUM	0	Bark	not available	95600.0	not available	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
HOLADIENE	0	Stem Bark	not available	7.0	not available	Siddiqui, B. S., Usmani, S. B., Begum, S., Siddiqui, S. 1993. Steroidal Alkaloids and an Androstane Derivative from the Bark of Holarrhena pubescens. Phytochemistry, 33(4): 925-928.
HOLADYSONE	0	Bark	not available	1.3	not available	Duke, 1992 *
HOLAMIDE	0	Bark	not available	2.5	not available	Siddiqui, B. S., Usmani, S. B., Begum, S., Siddiqui, S., Aftab, K., Gilani, A. U. 1995. Hypotensive Constituents from the Bark of Holarrhena pubescens (Holarrhena antidysenterica). Heterocycles, 41(2): 267-276.
HOLARRHENINE	3	Bark	not available	not available	not available	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
HOLARRHESSIMINE	0	Bark	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
HOLARRHIDINE	0	Bark	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
HOLARRHIMINE	0	Bark	not available	not available	not available	Duke, 1992 *
HOLARRHIMINE	0	Seed	not available	not available	not available	Duke, 1992 *
HOLARRHIMINE	0	Stem Bark	not available	not available	not available	Duke, 1992 *
HOLARRHINE	0	Bark	not available	not available	not available	Duke, 1992 *
HOLARRHINE	0	Seed	not available	not available	not available	Duke, 1992 *
HOLARRICINE	0	Seed	not available	not available	not available	Duke, 1992 *
HOLARRIFINE	0	Bark	not available	not available	not available	Duke, 1992 *
HOLONAMINE	0	Bark	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.

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List of plant activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Chemical Count	Reference
Potassium-Sparing	1	Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Proliferant	1	Duke, 1992 *
Propecic	4	Duke, 1992 *
Prostaglandin-Synthesis-Inhibitor	1	Ibewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284.
Protease-Inhibitor	1	Duke, 1992 *
Protein-Kinase-C-Inhibitor	1	Naim, M., Zehavi, U., Nagy, S., and Rouseff, R.L. Hydroxycinnamic Acids as Off-Flavor Precursors in Citrus Fruits and Their Products. Phenolic Compounds in Food and Their Effects on Health, Ch.14.
Protisticide	3	Chemical Express, 7: 285, 1992.
Psychotropic	1	Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
PTK-Inhibitor	1	Duke, 1992 *
Quinone-Reductase-Inducer	3	Duke, 1992 *
Sedative	1	Duke, 1992 *
Soap	1	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Sodium-Sparing	1	Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Spermicide	1	Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Suppository	1	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Teratologic	2	Duke, 1992 *
TNF-alpha-Inhibitor	2	Duke, 1992 *
TOPO-2-Inhibitor	2	Duke, 1992 *
Topoisomerase-I-Inhibitor	2	Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor	2	Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225.