Dianthus caryophyllus | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Carnation, Clavel (Sp.), Clove Pink, Nelke (Ger.), Oeillet (Fr.)

How used

Medicinal

Data Views

Activities: 134

Chemicals w/Activities: 12

All Chemicals: 27

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List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	3,5-DI-O-(BETA-GLUCOPYRANOSYL)-CYANIDIN-6''-O-4,6'''-O-1-CYCLIC-MALATE	Flower	--	--	--	*
0	3,5-DI-O-(BETA-GLUCOPYRANOSYL)-PELARGONIDIN-6''-O-4,6'''-O-1-CYCLIC-MALATE	Flower	--	--	--	*
30	ANTHOCYANINS	Flower	--	--	--	*
Antiapoptotic * Antiarthritic 120 mg/man orl * Anticancer 120 mg/man orl * Anticarcinogenic * Anticollegenase * Antidiabetic * Antielastase * Antihyperglycemic * Antihyperinsulinemic * Antihyperleptinemic * Antiinflammatory * Antimutagenic * Antimyopic 600 mg/man orl * Antinyctalopic 600 mg/man orl * Antiobesity * Antioxidant * Antiproliferant * Antitumor 120 mg/man orl * Antivaricose * Antiviral * Chemopreventive * COX-1-Inhibitor IC45=125 ug/ml * COX-2-Inhibitor IC47=125 ug/ml * Goitrogenic * Hemostat * NO-Scavenger * Pesticide * Vasoactive * Vasodilator * Vasoprotective *
17	BENZYL-BENZOATE	Flower	3.0	1160.0	1.96	*
Acaricide LD50=9.22 ug/sq cm cf DEET at 37.59 ug/sq cm * Allergenic Martindale's 29th Antiasthmatic * Antidysmenorrheic * Antispasmodic * Antitumor ED50=8-15 Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Artemicide LC50=2 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. CNS-Depressant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. CNS-Stimulant Martindale's 29th FLavor FEMA 40-300 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hypotensive Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Insectifuge Martindale's 29th Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Myorelaxant * Pediculicide Martindale's 29th Pesticide * Scabicide Merck 11th Edition
2	BENZYL-SALICYLATE	Flower	2.0	145.0	1.41	*
Allergenic * FLavor FEMA <1 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
0	CIS-HEXENYL-BENZOATE	Flower	0.3	320.0	--	*
0	CYANIDIN-3,5-GLUCOSIDE	Flower	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
0	CYANIDIN-3-GLUCOSIDE	Flower	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
0	CYANIDINS	Flower	--	--	--	*
4	DIANTHIN-30	Leaf	--	--	--	*
AntiHIV 100 ug/ml * Antiproteinigenic 100 ug/ml * Antiribosomal 100 ug/ml * Antiviral 100 ug/ml *
4	DIANTHIN-32	Leaf	--	--	--	*
AntiHIV 100 ug/ml * Antiproteinigenic 100 ug/ml * Antiribosomal 100 ug/ml * Antiviral 100 ug/ml *
0	EO	Flower	30.0	2900.0	-0.33	*
76	EUGENOL	Flower	0.6	870.0	-0.37	*
Acaricide LD50=5.47 ug/sq cm cf DEET at 37.59 ug/sq cm * Allergenic * Analgesic Merck 11th Edition Anesthetic 200-400 Phytotherapy Research, 4: 93. Antiaggregant IC50=0.3 uM Phytotherapy Research, 4: 93. Antiarachidonate * Antibacterial 500 ppm Valnet, J. 1982. The Practice of Aromatherapy. Translated from the 1980 French Edition by Robin Campbell and Libby Houston. Destiny Books, New York. 279 pp. Antibacterial MBC=400 ug/ml * Anticonvulsant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiedemic 100 Phytotherapy Research, 4: 95. Antiestrogenic * Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antigenotoxic 50-500 mg/kg orl mus * Antiherpetic IC50=16.2-25.6 ug/ml * Antiinflammatory (11 uM) IC~97=1,000 uM * Antikeratotic IC50=16.2-25.6 ug/ml * Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antinitrosating * Antioxidant IC65=30 ppm * Antioxidant 10 uM * Antiprostaglandin IC50=9.2 mM * Antiprostaglandin 11 uM * Antipyretic 3 ml/man/day * Antiradicular EC50=2 ul/l * Antisalmonella MIC=400 ug/ml * Antiseptic 400 ug/ml * Antiseptic 3 ml/man/day * Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antithromboxane Lawrence Review of Natural Products, Jul-87. AntiTNF * Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992. Antiulcer * Antiviral IC50=16.2-25.6 ug/ml * Apifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Calcium-Antagonist IC50=224 uM * Calcium-Antagonist IC50=200 uM gpg * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Phytotherapy Research, 4: 93. Carcinogenic? Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Choleretic * CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. COX-1-Inhibitor IC97=1,000 uM * COX-2-Inhibitor IC>97=1,000 uM * COX-2-Inhibitor IC50=129 uM * Cytochrome-P450-Inhibitor Pizzorno, J. 1998. Total Wellness. Prima Health, a division of Prima. Cytotoxic 25 ug/ml Phytotherapy Research, 4: 93. Dermatitigenic * Enterorelaxant J. Aromatherapy 4: 22. FLavor FEMA 10-500 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide * Hepatoprotective 100 ppm * Herbicide * Insecticide * Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Irritant * Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Larvicide * Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Nematicide MLC=2,000 ug/ml Shoyakugaku Zasshi, 44: 183. Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Prostaglandin-Synthesis-Inhibitor 1 mM rbt Chen, S. J., Wang, M. H., Chen, I. J. 1996. Antiplatelet and Calcium Inhibitory Properties of Eugenol and Sodium Eugenol Acetate. Gen Pharmacol, 27(4): 629-633. Prostaglandin-Synthesis-Inhibitor IC50=9.2 uM * Sedative * Termiticide LD100=5 mg/g * Trichomonicide LD100=300 ug/ml * Trichomonistat IC50=10 ug/ml Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Trypsin-Enhancer Lawrence Review of Natural Products, Dec-93. Ulcerogenic Phytotherapy Research, 4: 93. Varroacide * Vasodilator * Vermifuge *
0	HEPTACOSANE	Flower	--	--	--	Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
0	ISOLYCHNOSE	Seed	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
1	KAEMPFERIDE-TRIGLYCOSIDE	Plant	--	--	--	*
Fungicide *
0	LAKTORINE	Root	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
0	LYCHNOSE	Seed	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
21	METHYL-SALICYLATE	Flower	--	29.0	1.41	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Allergenic Martindale's 28th Analgesic * Anaphrodisiac * Antiinflammatory Planta Medica, 56(6): 660, 1990. Antioxidant * Antipyretic * Antiradicular O'Connell, M.J., Webster, N.R. 1989. Hyperoxia and salicylate metabolism in rats. J. Pharm. Pharmacol. 42: 205-206, 1990. Antirheumatalgic Martindale's 28th Antiseptic * Antitartar * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carminative * Counterirritant Merck 11th Edition Dentifrice Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry FLavor FEMA 70-8,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide * Herpetifuge * Insectifuge Hardie, J., Isaacs, R., Pickett,* J.A., Wadhams, L.J., and Woodcock, C.M. 1994. Methyl Salicylate and (-)-(1R,5S)-Myrtenal are Plant-Derived Repellents for Black Bean Aphid, Aphis Fabae Scop. (Homoptera: Aphididae). J. of Chemical Ecology, 20(11):2847. Insectiphile * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide *
24	PECTIN	Root	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Antiatheromic 15 g/man/day Cerda, J.J. Pectin in Health and Disease. HortScience, 25(12): 1485, 1990. Antibacterial * Antidiabetic 10 g/man/day/orl * Antidiarrheic Merck 11th Edition Antienteritic * Antigallstone * Antigastritic * Antilithic * Antimetastatic * Antimutagenic * Antiobesity Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Antitumor (Colon) * Antitumor (Prostate) * Antitussive * Antiulcer * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Chemopreventive * Demulcent * Fungicide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Hemostat * Hypocholesterolemic * Hypoglycemic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Peristaltic * Pesticide *

List of all activity chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Dianthus caryophyllus (Caryophyllaceae)

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