Costus speciosus | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Cane Reed, Crepe Ginger, Wild Ginger

How used

Medicinal

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Activities: 168

Chemicals w/Activities: 9

All Chemicals: 21

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	14-OXO-HEPTACOSANOIC-ACID	Plant	--	--	--	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
0	14-OXO-TRICHOSANOIC-ACID	Plant	--	--	--	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
0	15-OXO-OCTACOSANOIC-ACID	Plant	--	--	--	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
0	5-ALPHA-STIGMAST-9(11)-EN-3-BETA-OL	Plant	--	--	--	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
47	BETA-SITOSTEROL	Rhizome	--	--	--	*
Androgenic * Angiogenic * Anorexic Martindale's 28th Antiadenomic Merck 11th Edition Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Anticancer (Cervix) * Anticancer (Lung) * Antiedemic IC54=320 mg/kg orl * Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * Antileukemic * Antilymphomic * Antimutagenic 250 ug/ml * Antiophidic 2.3 mg mus Economic & Medicinal Plant Research, 5: 363. Antioxidant IC44=10 uM * Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antiprostaglandin 30 mg/day/12 wks * Antiprostatadenomic Merck 11th Edition Antiprostatitic 10-20 mg 3 x/day/orl man * Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Antitumor (Cervix) * Antitumor (Lung) * Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991. Apoptotic * Artemicide LC50=110 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Caspase-8-Inducer * Estrogenic * Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Hepatoprotective * Hypocholesterolemic 2-6 g/man/day/orl Martindale's 30th Hypocholesterolemic 9-3,330 mg/man/day/orl Martindale's 28th Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypolipidemic 2-6 g/day * Pesticide * Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Ulcerogenic 500 mg/kg ipr rat *
0	BETA-SITOSTEROL-GLUCOSIDE	Rhizome	--	--	--	*
0	CORTICOSIDE-I	Plant	--	--	--	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
0	CORTICOSIDE-J	Plant	--	--	--	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
135	CURCUMIN	Rhizome	--	--	--	*
12-Lipoxygenase-Inhibitor * 5-Alpha-Reductase-Inhibitor * 5-HETE-Inhibitor IC50=3-10 uM * 5-Lipoxygenase-Inhibitor * 8-HETE-Inhibitor IC40=3 uM * Antiadenomacarcinogenic 50-200 mg/kg ipr rat * Antiaflatoxin IC50=81 uM * Antiaggregant * Antialzheimeran 0.5-10 ug/ml * Antiamyloid-Beta 0.5-10 ug/ml * Antiangiogenic * Antiarachidonate * Antiarthritic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiasthmatic * Antiatherosclerotic 0.4-20 mg/kg/day * Antibacterial Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Antibronchitic * Anticancer * Anticancer (Breast) * Anticancer (Colon) * Anticancer (Duodenum) * Anticancer (Mammary) 50-200 mg/kg ipr rat * Anticancer (Skin) * Anticancer (Stomach) * Anticarcinogenic * Anticataract 75 mg/kg orl rat * Anticholecystosic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticolitic * Anticollagenic * AntiCrohn's * AntiEBV IC50=5.4 uM * Antieczemic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Antiedemic ED50=48 mg/kg orl rat (cf 48 for phenylbutazone) * Antiedemic ED50=100.2 mg/kg orl mus (cf 78 for cortisone) * Antiedemic ED50=48 mg/kg orl rat (cf 45 for cortisone) * Antieicosanoid * Antihepatotic * AntiHIV IC50=40 uM * Antiinflammatory 1 uM * Antiinflammatory 1,200 mg/man/day * Antiintegrase 40-150 uM * Antiischemic * Antileishmanic IC50=7.8 ug/ml * Antileukemic * Antileukotriene 170 mg/kg orl rat * Antilipoperoxidant * Antilithic 0.5% diet * Antilymphomic 4 ug/ml Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antilymphomic 0.4 mg/ml Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Antimelanomic 200 nM/kg orl mus * Antimetastatic 200 nM/kg orl mus * Antimutagenic * Antinitrosaminic * Antioxidant 1/3 BHA * Antioxidant IC50=500 uM * Antipapillomic * Antiperoxidant * Antiproliferant IC50=13 uM * Antiprostaglandin 8.8 uM * Antipsoriatic * Antispasmodic =ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp Antithrombotic * Antithromboxane * Antitumor * Antitumor (Colon) * Antitumor (Liver) 10 uM * Antitumor-Promoter IC91=10 uM * Antiulcer orl rat * Antiviral IC50=5.4 uM * Apoptotic 150-2,000 ppm (diet) orl rat * Apoptotic 30-90 uM * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiodepressant =ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp Chelator Iron * Chelator IC50=500 uM * Chemopreventive * Cholagogue * Choleretic HerbalGram No. 24, page 37. COX-2-Inhibitor 10-20 uM * Cyclooxygenase-Inhibitor * Cytochrome-P450-Inhibitor Pizzorno, J. 1998. Total Wellness. Prima Health, a division of Prima. Cytotoxic IC50=25 uM * Cytotoxic IC50=1 ug/ml * Cytotoxic 0.4-4 mg/ml Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Deodorant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Detoxicant * DNA-Protective * Dye Merck 11th Edition Expectorant 100 uM * Fibrinolytic * Fungicide * Glutathionigenic 80 mg/kg igs rat * Hepatoprotective 30 mg/kg/day * Hepatoprotective 30 ppm * Hypocholesterolemic 0.15% diet 7 wks * Hypolipidemic 0.15% diet 7 wks * Hypotensive * IkappaB-alpha-Phosphorylation-Inhibitor * IKB-kinase-Inhibitor * IKK-Inhibitor * Immunostimulant 40 mg/kg/5 wk orl rat * Lipase-Inducer * Litholytic 0.5% diet * Maltase-Promoter * MDR-Inhibitor 1-55 uM * Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25. MMP-9-Inhibitor 10 uM * Mucogenic 100 uM * Nematicide * Neuroprotective 80 mg/kg igs rat * NF-kB-Inhibitor * NO-Inhibitor * NO-Scavenger * Ornithine-Decarboxylase-Inhibitor ED=~150 mg/kg * P450-Inhibitor IC50=2-14 ug/ml * Pesticide * PGE2-Inhibitor IC42=3 uM * Phototoxic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Plasmodicide * Prostaglandin-Synthesis-Inhibitor 0.2% diet rat Rao, C. V., Rivenson, A., Simi, B., Reddy, B. S. 1995. Chemoprevention of Colon Carcinogenesis by Dietary Curcumin, a Naturally Occurring Plant Phenolic Compound. Cancer Research, 55(2): 259-266. Protease-Inhibitor IC50=11-250 uM * Protein-Kinase-C-Inhibitor IC69=15 uM * Protein-Kinase-C-Inhibitor IC50=15 uM * Protein-Kinase-Inhibitor * PTK-Inhibitor 5-100 uM * Pulmonoprotective 200 mg/kg/7 d * Quinone-Reductase-Inducer 3.4 uM Singletary, K., et al. 1998. Effect of the Beta-Diketones Diferoloylmethane (Curcumin) and Dibenzoylmethane on Rat Mammary DNA Adducts and Tumors Induced by 7,12-dimethylbenz(A)anthracene. Carcinogenesis, 19(6): 1039-1043. Radioprotective * Sortase-A-Inhibitor IC50=13-14 ug/ml * Sucrase-Promoter * TNF-Inhibitor * Topoisomerase-I-Inhibitor * Topoisomerase-II-Inhibitor * Ulcerogenic orl rat * VEGF-Inhibitor *
9	CURCUMINOIDS	Rhizome	--	30000.0	1.00	*
Anticancer Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Antiinflammatory Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Antileukotriene Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Antimitotic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Antiprostaglandin Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Antitumor Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Cytotoxic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Ulcerogenic? Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
7	DIOSGENIN	Rhizome	--	--	--	*
Antifatigue * Antiinflammatory * Antistress * Estrogenic 20-40 mg/kg/day/15 day scu mus * Hepatoprotective * Hypocholesterolemic * Mastogenic 20-40 mg/kg/day/15 day scu mus *
0	DISOCIN	Rhizome	--	--	--	*
1	GRACILLIN	Rhizome	--	--	--	*
Hemolytic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
3	MUCILAGE	Rhizome	--	--	--	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Demulcent * Hypocholesterolemic *
5	STARCH	Rhizome	--	333333.0	-0.64	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Absorbent Martindale's 29th Antidote (Iodine) Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antinesidioblastosic Martindale's 29th Emollient Martindale's 29th Poultice Martindale's 29th
0	STEROID SAPONINS	Rhizome	10000.0	40000.0	--	*
0	TETRADECYL-11-METHYLTRIDECANOATE	Plant	--	--	--	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
0	TETRADECYL-13-METHYLPENTADECANOATE	Plant	--	--	--	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
1	TIGOGENIN	Rhizome	--	--	--	*
Antitumor *
0	TRIACONTANOIC-ACID	Plant	--	--	--	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Costus speciosus (Costaceae)

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