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Plant Panax notoginseng (Araliaceae)
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Common name(s)
Sanchi Ginseng
How used
Medicinal
Data Views
| # Activity | Chemical Name | Part | Low PPM | High PPM | StdDev | *Reference |
|---|---|---|---|---|---|---|
| 0 | (20)-PROTOPANAXADIOL | Root | -- | -- | -- | * |
| 0 | (20)-PROTOPANAXATRIOL | Root | -- | -- | -- | * |
| 47 | BETA-SITOSTEROL | Root | -- | -- | -- | * |
|
Androgenic
*
Angiogenic
*
Anorexic
Martindale's 28th
Antiadenomic
Merck 11th Edition
Antiandrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
*
Anticancer (Lung)
*
Antiedemic IC54=320 mg/kg orl
*
Antiestrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
*
Antileukemic
*
Antilymphomic
*
Antimutagenic 250 ug/ml
*
Antiophidic 2.3 mg mus
Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
*
Antiprogestational
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
*
Antiprostatadenomic
Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
*
Antipyretic
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
*
Antitumor (Lung)
*
Antiviral
Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
*
Artemicide LC50=110 ppm
Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
*
Estrogenic
*
Febrifuge
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
*
Hypocholesterolemic 2-6 g/man/day/orl
Martindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orl
Martindale's 28th
Hypoglycemic
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
*
Pesticide
*
Spermicide
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
*
|
||||||
| 5 | DAUCOSTEROL | Root | -- | -- | -- | * |
|
Aldose-Reductase-Inhibitor 0.1 mM/l rat (weak activity, 31.9% inhibition)
Fujita, T., Ohira, K., Miyatake, K., Nakano, Y., Nakayama, M. 1995. Inhibitory Effect of Perillosides A and C, Related Monoterpene Glucosides on Aldose Reductase and Their Structure-Activity Relationships. Chem Pharm Bull, 43(6): 920-926.
Antileukemic
*
Antispasmodic 20 mg/kg
=ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp
Antitumor
*
Hypoglycemic
Economic & Medicinal Plant Research, 6: 158.
|
||||||
| 0 | GINSENOSIDE-RA | Root | -- | -- | -- | * |
| 1 | GINSENOSIDE-RB | Root | -- | -- | -- | * |
|
Antimyocarodtic
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
|
||||||
| 14 | GINSENOSIDE-RB-1 | Root | -- | -- | -- | * |
|
Antiamnesic
Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Antipsychotic
Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Antistress
Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Antitumor
Economic & Medicinal Plant Research, 6: 189.
Antiulcer
Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Calcium-Antagonist 200 uM
*
CNS-Sedative
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Corticosteroidogenic 70 mg/kg
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hypoglycemic
*
Hypothermic
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
MDR-Inhibitor 100 uM cat
Hasegawa,H.,Sung,J.H.,Matsumiya,S.,Uchiyama,M.,Inouye,Y.,Kasai,R.,Yamasaki,K. 1995. Reversal of Daunomycin and Vinblastine Resistance in Multidrug-Resistance P388 Leukemia in vitro through Enhanced Cytotoxicity by Triterpenoids. Planta Med, 61(5):409-413.
Neurogenic
*
Tranquilizer
Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Vasodilator
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
|
||||||
| 8 | GINSENOSIDE-RB-2 | Root | -- | -- | -- | * |
|
Calcium-Antagonist 200 uM
*
Corticosteroidogenic 35 mg/kg
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hypocholesterolemic 10 mg/kg/day ipr rat
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypoglycemic 10 mg/kg/day ipr rat
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypotriglyceridemic 10 mg/kg/day ipr rat
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Lipolytic 10 mg/kg/day ipr rat
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
MDR-Inhibitor 100 uM
Hasegawa,H.,Sung,J.H.,Matsumiya,S.,Uchiyama,M.,Inouye,Y.,Kasai,R.,Yamasaki,K. 1995. Reversal of Daunomycin and Vinblastine Resistance in Multidrug-Resistance P388 Leukemia in vitro through Enhanced Cytotoxicity by Triterpenoids. Planta Med, 61(5):409-413.
Proteinogenic
*
|
||||||
| 5 | GINSENOSIDE-RE | Root | -- | -- | -- | * |
|
Analgesic 10 mg/kg mus
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Calcium-Antagonist 200 uM
*
Corticosteroidogenic 35 mg/kg
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
MDR-Inhibitor 100 uM
Hasegawa,H.,Sung,J.H.,Matsumiya,S.,Uchiyama,M.,Inouye,Y.,Kasai,R.,Yamasaki,K. 1995. Reversal of Daunomycin and Vinblastine Resistance in Multidrug-Resistance P388 Leukemia in vitro through Enhanced Cytotoxicity by Triterpenoids. Planta Med, 61(5):409-413.
Vasodilator
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
|
||||||
| 13 | GINSENOSIDE-RG-1 | Root | -- | -- | -- | * |
|
Antiaggregant
*
Antifatigue
Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antistress
Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Aphrodisiac
*
Calcium-Antagonist 200 uM
*
CNS-Stimulant
Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Homeostatic
*
Hypoglycemic
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
MDR-Inhibitor 100 uM
Hasegawa,H.,Sung,J.H.,Matsumiya,S.,Uchiyama,M.,Inouye,Y.,Kasai,R.,Yamasaki,K. 1995. Reversal of Daunomycin and Vinblastine Resistance in Multidrug-Resistance P388 Leukemia in vitro through Enhanced Cytotoxicity by Triterpenoids. Planta Med, 61(5):409-413.
Pyrogenic 50 mg/kg ipr mus
Takagi, K. 1977. Pharmacological Studies on Ginseng. Korean Ginseng Studies, Il Hwa Co., Ltd., Seoul, South Korea, 1977: 346-357.
Stimulant
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Vasodilator
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
|
||||||
| 3 | GINSENOSIDE-RG-2 | Root | -- | -- | -- | * |
|
Antiaggregant
*
Calcium-Antagonist 60-200 uM
*
MDR-Inhibitor 100 uM
Hasegawa,H.,Sung,J.H.,Matsumiya,S.,Uchiyama,M.,Inouye,Y.,Kasai,R.,Yamasaki,K. 1995. Reversal of Daunomycin and Vinblastine Resistance in Multidrug-Resistance P388 Leukemia in vitro through Enhanced Cytotoxicity by Triterpenoids. Planta Med, 61(5):409-413.
|
||||||
| 18 | GINSENOSIDES | Root | -- | 87000.0 | 1.40 | * |
|
Adaptogenic
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiaggregant
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Anticancer
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antidiuretic 126 mg/kg
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antishock
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Calcium-Antagonist
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Corticosterogenic
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Ethanolytic
*
Gonadotrophic
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hypocholesterolemic
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hypoglycemic
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hypotensive
*
Immunomodulator
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Interferonogenic
*
Lactogenic
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Mycorelaxant
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Phagocytotic
*
Thyrotropic
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
|
||||||
| 0 | NOTOGINSENOSIDES | Root | -- | -- | -- | * |
| 0 | PANAXYNAL | Root | -- | -- | -- | * |
| 176 | QUERCETIN | Root | -- | -- | -- | * |
|
11B-HSD-Inhibitor
*
5-Lipoxygenase-Inhibitor IC50 (uM)=4
*
Aldehyde-Oxidase-Inhibitor IC70-96=10 uM
*
Aldose-Reductase-Inhibitor 4 ug/ml
Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Aldose-Reductase-Inhibitor IC50=0.84 ug/ml cow
Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Aldose-Reductase-Inhibitor IC50=0.344 uM
Mao, X. M., Zhang, J. Q. 1993. Inhibition of Aldose Reductase by Extracts of Chinese Herbal Medicine. Zhongguo Zhongyao Zazhi , 18(10): 623-624.
Aldose-Reductase-Inhibitor 100 uM
*
Allelochemic IC82=1 mM
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Allergenic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Analgesic
*
Antiaflatoxin IC50=25 uM
*
Antiaflatoxin IC50=7.5 ppm
*
Antiaggregant IC50=55 uM
Economic & Medicinal Plant Research, 5: 333.
Antiaggregant 30 uM
*
Antiaging
*
Antiallergic IC50=14 uM
Jim Duke's personal files.
Antialzheimeran
*
Antianaphylactic
Meli, R., Autore, G., Di Carlo, G., Capasso, F. Inhibitory Action of Quercetin on Intestinal Transit in Mice. Phytotherapy Research 4(5): 201, 1990.
Antiangiogenic
*
Antiarthritic
*
Antiasthmatic IC50=14 uM
*
Antiatherosclerotic
*
Antibacterial
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic (Breast) IC50=1.5 uM
Medline (post 1990 searches filed in my computer)
Anticariogenic ID50=120 ug/ml
*
Anticataract
*
Anticolitic 400 mg/man/3x/day
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticomplementary
*
AntiCrohn's 400 mg/man/3x/day
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticystitic 1,000 mg/day/4 weeks
*
Antidepressant
*
Antidermatitic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antidiabetic
*
Antielastase IC50=0.8 ug/ml
*
Antiencephalitic
Economic & Medicinal Plant Research, 5: 199.
Antiescherichic
*
Antiestrogenic
*
Antifeedant IC52=<1,000 ppm diet
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antifibrosarcomic
*
Antiflu
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antigastric
Rastitel'nye Resursy, 21: 85.
Antigonadotropic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
AntiGTF ID50=120 ug/ml
*
Antihepatotoxic
Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
Antiherpetic 48-150 ug/ml
*
Antihistaminic IC50=<10 uM
*
AntiHIV
*
Antihydrophobic
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antihypertensive
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20-150 mg/kg
Fitoterapia No.5-1990.
Antileishmanic IC50=64
*
Antileukemic IC50=10 uM
Economic & Medicinal Plant Research, 5: 225.
Antileukemic IC50=>10 ug/ml
Life Sciences 55: 1061.
Antileukemic 5.5-60 uM
*
Antileukotriene
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antilipoperoxidant IC67=50
*
Antimalarial IC50=1-6.4 ug/ml
Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antimelanomic
*
Antimetastatic
*
Antimutagenic ID50=0.62 ug/ml
*
Antimutagenic ID50=2-5 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimyocarditic
Economic & Medicinal Plant Research, 5: 199.
Antinitrosaminic
*
Antinociceptive
*
Antioxidant ED50=2.3 uM
Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antioxidant IC47=10 uM
*
Antioxidant IC96=300 ppm
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant 4.7 x Vit. E
*
Antipancreatitic
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiperiodontal
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiperistaltic
*
Antipermeability
*
Antiperoxidant
Planta Medica, 57: A110, 1991.
Antipharyngitic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplaque
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplasmodial IC50=13-64
*
AntiPMS 500 mg/2x/day/wmn
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antipodriac
*
Antipolio
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiproliferant 10 nM
*
Antiprostanoid
*
Antiprostatitic
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antipsoriac
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiradicular IC50=4.6 uM
Planta Medica, 56(6): 695, 1990.
Antispasmodic
*
Antistreptococcic ID50=120 ug/ml
*
Antithiamin
Phenolic Compounds in Food and Their Effects on Health, 69.
Antithrombic
*
Antitrypanosomic IC50=13
*
Antitumor 10 uM
*
Antitumor (Bladder)
*
Antitumor (Breast)
*
Antitumor (Colon)
*
Antitumor (Lung)
*
Antitumor (Ovary)
*
Antitumor (Skin) 20 uM
*
Antitumor-Promoter
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiulcer
*
Antiviral IC50=10 uM
Economic & Medicinal Plant Research, 5: 225.
Antiviral 48-150 ug/ml
Amoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Apoptotic 20-60 uM
*
ATPase-Inhibitor
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Bacteristat 10 mg/ml
*
Bradycardiac
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Calmodulin-Antagonist
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
cAMP-Phosphodiesterase-Inhibitor
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
*
Capillariprotective
Merck 11th Edition
Carcinogenic 40,000 ppm (diet) mus
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Catabolic
*
COMT-Inhibitor
*
Copper-Chelator
*
COX-2-Inhibitor <40 uM
*
Cyclooxygenase-Inhibitor
*
Cytochrome-P450-1A2-Inhibitor
*
Cytotoxic ED50=70 ug/ml
Matsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
Cytotoxic IC82=100 ug/ml
Planta Medica, 57: A113, 1991.
Deiodinase-Inhibitor
Jim Duke's personal files.
Diaphoretic?
Lawrence Review of Natural Products, Dec-90.
Differentiator 5.5 uM
*
Estrogenic 10% genistein
*
Fungicide
*
Glucosyl-Transferase-Inhibitor ID50=120 ug/ml
*
Hemostat
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hepatomagenic 5,000 ppm (diet) rat
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective
*
HIV-RT-Inhibitor IC50=<1 ug/ml
Nakane, H., Fukushima, M., and Ono*, K. Differential Inhibition Of Reverse Transcriptase And Various DNA Polymerases By Digallic Acid And Its Derivatives. Journal of Natural Products, 53(5): 1234-1240, 1990.
Hypoglycemic 100 mg/kg orl rat
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
iNOS-Inhibitor IC50=20 uM
*
Inotropic
*
Insulinogenic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Juvabional
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Larvistat 8,000 ppm diet
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC11=1.25 mM
Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=0.1-5 uM
*
MAO-A-Inhibitor
*
Mast-Cell-Stabilizer
*
Metal-Chelator (Copper)
Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Metalloproteinase-Inhibitor IC50=>42 uM
*
MMP-9-Inhibitor 20 uM
*
Mutagenic
*
NADH-Oxidase-Inhibitor
*
NEP-Inhibitor IC50=>42 uM
*
Neuroprotective 5-25 uM
*
NF-kB-Inhibitor
*
NO-Inhibitor IC50=20 uM
*
NO-Inhibitor IC>50=125 uM
*
NO-Synthase-Inhibitor 5-50 uM
*
Ornithine-Decarboxylase-Inhibitor <10 uM
*
P450-Inducer 5 uM
Father Nature's Farmacy: The aggregate of all these three-letter citations.
P450-Inhibitor 50-100 uM
Father Nature's Farmacy: The aggregate of all these three-letter citations.
Pesticide
*
PGE2-Inhibitor
*
Phospholipase-Inhibitor
*
Plasmodicide
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Proliferant
*
Prostaglandin-Synthesis-Inhibitor 40 ug/ml
Ibewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284.
Protein-Kinase-C-Inhibitor
Naim, M., Zehavi, U., Nagy, S., and Rouseff, R.L. Hydroxycinnamic Acids as Off-Flavor Precursors in Citrus Fruits and Their Products. Phenolic Compounds in Food and Their Effects on Health, Ch.14.
PTK-Inhibitor 0.4-24 uM
*
Quinone-Reductase-Inducer 13 uM
*
Quinone-Reductase-Inducer 6 uM
Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Teratologic
*
TNF-alpha-Inhibitor IC50=3.11 uM
*
Topoisomerase-I-Inhibitor IC50=42 uM
*
Topoisomerase-I-Inhibitor IC50=12.8 ug/ml
*
Topoisomerase-II-Inhibitor IC50=23-40 uM
*
Topoisomerase-II-Inhibitor IC50=1-6.9 ug/ml
*
Tumorigenic 0.1% diet orl rat/yr
Jim Duke's personal files.
Tyrosinase-Inhibitor ID50=70 uM
*
Tyrosine-Kinase-Inhibitor
Economic & Medicinal Plant Research, 6: 170.
Vasodilator
*
VEGF-Inhibitor
*
Xanthine-Oxidase-Inhibitor 3.1 uM
*
Xanthine-Oxidase-Inhibitor IC50=>0.4 ug/ml
Chem. & Pharm. Bull. 38: 1772.
Xanthine-Oxidase-Inhibitor IC50=10.6 ug/ml
*
|
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| # Activity | Chemical Name | Part | Low PPM | High PPM | StdDev | *Reference |
|---|
| # Chemical | Activity Name | *Reference |
|---|---|---|
 |
||
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.