Melaleuca leucadendra | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Cajeput

How used

Medicinal

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Activities: 236

Chemicals w/Activities: 21

All Chemicals: 32

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	3,5-DIMETHYL-4,6-DI-O-METHYLPHLORACETOPHENONE	Leaf	--	1300.0	--	*
28	ALPHA-PINENE	Leaf	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Allelochemic * Allergenic * Antiacne * Antibacterial * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory 500 mg/kg * Antipneumonic * Antiseptic * Antispasmodic * Antistaphylococcic * Antiviral Economic & Medicinal Plant Research, 5: 195. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Coleoptophile * Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. FLavor FEMA 15-150 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide IC50=30 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insecticide 0.82 uM/fly * Insectifuge 50 ppm * Insectiphile J. Stored. Prod. Res., 22:141, 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. P450-2B1-Inhibitor IC50=0.087 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Sedative Lawrence Review of Natural Products, Jun-90. Spasmogenic * Tranquilizer Lawrence Review of Natural Products, Jun-90. Transdermal *
28	ALPHA-PINENE	Plant	--	--	--	*
Allelochemic * Allergenic * Antiacne * Antibacterial * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory 500 mg/kg * Antipneumonic * Antiseptic * Antispasmodic * Antistaphylococcic * Antiviral Economic & Medicinal Plant Research, 5: 195. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Coleoptophile * Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. FLavor FEMA 15-150 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide IC50=30 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insecticide 0.82 uM/fly * Insectifuge 50 ppm * Insectiphile J. Stored. Prod. Res., 22:141, 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. P450-2B1-Inhibitor IC50=0.087 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Sedative Lawrence Review of Natural Products, Jun-90. Spasmogenic * Tranquilizer Lawrence Review of Natural Products, Jun-90. Transdermal *
23	ALPHA-TERPINEOL	Essential Oil	--	--	--	Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
ACE-Inhibitor 100 ug/ml (weak activity) * Aldose-Reductase-Inhibitor 100 ug/ml Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antiacne * Antibacterial MIC=800-1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticariogenic MIC=800-1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Antiinflammatory * Antiproliferant * Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cicatrizant ED50=240 ug/g mus * FLavor FEMA 5-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Insecticide 1.29 uM/fly * Interleukin-6-Inhibitor * Mosquitofuge > Deet * Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Termiticide IC100=5 mg/g * Transdermal * Vulnerary ED50=240 ug/g mus *
10	AZULENE	Essential Oil	--	--	--	Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Antiallergic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Antibacterial 500 ppm Valnet, J. 1982. The Practice of Aromatherapy. Translated from the 1980 French Edition by Robin Campbell and Libby Houston. Destiny Books, New York. 279 pp. Antihistaminic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiinflammatory Pakistan Encyclopedia Planta Medica. 1986. Antipyretic HerbalGram No. 20, page 40. Antiseptic 6-500 Valnet, J. 1982. The Practice of Aromatherapy. Translated from the 1980 French Edition by Robin Campbell and Libby Houston. Destiny Books, New York. 279 pp. Antispasmodic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiulcer ED50=150 (orl) * Hepatoregenerative Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Pesticide *
24	BENZALDEHYDE	Essential Oil	--	--	--	*
Allergenic * Anesthetic * Antibacterial * Anticancer * Antimutagenic * Antipeptic * Antiseptic * Antispasmodic * Antitumor * Candidicide * FLavor FEMA 150-800 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Immunostimulant * Insecticide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Insectifuge 50 ppm J. Stored. Prod. Res., 22:141, 1986. Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Narcotic Merck 11th Edition Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Pesticide * Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Termiticide LD100=5 mg/g * Tyrosinase-Inhibitor ID50=820 uM * Tyrosinase-Inhibitor ID50=87 ug/ml * Tyrosinase-Inhibitor ID50=0.82 mM * Tyrosinase-Inhibitor ID50=830 uM *
13	BETULIN	Bark	--	--	--	*
Anticarcinomic * Antifeedant * Antiflu * AntiHIV 6.1 uM * Antiinflammatory Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas. Planta Medica, 61: 9. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiviral 6.1 uM Aphidifuge Lugemwa, F.N., Huang, F-Y., Bentley, M.D., Mendel, M.J., and Alford, A.R. 1990. A Heliothis zea Antifeedant from the Abundant Birchbark Triterpene Betulin. J. Agric. Food Chem. 38(2): 493-494. Cytotoxic 8.6 uM * Cytotoxic 600 ppm * Hypolipemic * Prostaglandin-Synthesis-Inhibitor IC50=119 uM Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626. Topoisomerase-II-Inhibitor IC50=38.6 uM *
22	BETULINIC-ACID	Bark	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Anthelmintic * Antibacterial * Anticancer Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticarcinomic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiedemic * AntiHIV 14.8 uM * AntiHIV EC50=2.0 ug/ml Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095. AntiHIV IC50=6.5 ug/ml * Antiinflammatory Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas. Planta Medica, 61: 9. Antileukemic Antimalarial IC50=19-26 ug/ml * Antimelanomic New York Times, 3/28/95. Antinociceptive * Antiplasmodial IC50=19-26 ug/ml * Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiviral 14.8 uM * Apoptotic * Cytotoxic 16.4 uM * Cytotoxic 50-100 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al) Phospholipase-A2-Inhibitor * Prostaglandin-Synthesis-Inhibitor 200 ug/ml Dunstan, C. A., Liu, B., Welch, C. J., Perera, P., Bohlin, L. 1998. Alphitol, a Phenolic Substance from Alphitonia zizyphoides which Inhibits Prostaglandin Biosynthesis in vitro. Phytochemistry, 48(3): 495-497. Prostaglandin-Synthesis-Inhibitor IC50=101 uM Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
0	CAJEPUTOL	Essential Oil	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
0	CINEOLE	Leaf	1820.0	8450.0	0.64	*
7	DIPENTENE	Plant	--	--	--	*
Allergenic * Antibacterial Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antiviral Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sedative Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	EO	Leaf	--	13000.0	0.13	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
0	EO	Twig	--	13000.0	1.65	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
0	EPITARAXERY-ACETATE	Plant	--	--	--	*
2	FRIEDELIN	Plant	--	--	--	*
Antiinflammatory 30 mg/kg * Diuretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
62	GALLIC-ACID	Plant	--	--	--	*
ACE-Inhibitor IC50=7.7 mM/l * Analgesic * Antiadenovirus Economic & Medicinal Plant Research, 5: 194. Antiallergenic Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991. Antianaphylactic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiangiogenic * Antiasthmatic Watt, J.M., and Breyer-Brandwijk, M.G. The Medicinal and Poisonous Plants of Southern and Eastern Africa. 1962. Antibacterial MIC=1,000 ug/ml * Antibronchitic Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991. Anticancer * Anticarcinomic ED50=3 * Antiescherichic * Antifibrinolytic Economic & Medicinal Plant Research, 1: 53. Antiflu Economic & Medicinal Plant Research, 5: 194. Antihepatotoxic Okuda, T., Yoshida, T., and Hatano, T. Antioxidant Effects of Tannins and Related Polyphenols. Phenolic Compounds in Food and Their Effects on Health, Ch.7 p.93. Antiherpetic EC50=>10 ug/ml * AntiHIV * Antiinflammatory Kroes, B.H., et al. 1991. Anti-Inflammatory Activity of Gallic Acid. Planta Medica, 58(6): 499. Antileishmanic EC50=4.4 ug/ml * AntiMRSA * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antinitrosaminic * Antioxidant 7 x quercetin * Antioxidant IC44=33 ppm * Antioxidant 2/3 BHA * Antiperiodontitic 10 ug/ml * Antiperoxidant IC50=69 uM * Antipolio Economic & Medicinal Plant Research, 5: 194. Antiproteolytic 10 ug/ml * Antiradicular 7 x quercetin * Antiradicular IC50=4.9 uM * Antiseptic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antistaphylococcic MIC=1,000 ug/ml * Antitumor * Antitumor-Promoter * Antiviral * Apoptotic * Astringent Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Bacteristat Lamikanra, A., Ogundaini, A.O., and Ogungbamila, F.O. Antibacterial Constituents of Alchornea cordifolia Leaves. Phytotherapy Research 4(5): 198. Bronchodilator Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Carcinogenic * Choleretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cyclooxygenase-Inhibitor * Cytotoxic 500 uM * Floral-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Gram(+)icide MIC=1,000 ug/ml * Gram(-)icide MIC=1,000 ug/ml * Hemostat * Hepatoprotective Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Immunomodulator * Immunostimulant McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Immunosuppressant * Insulin-Sparing Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Myorelaxant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Nephrotoxic Martindale's 29th NO-Inhibitor IC-26=250 uM * Pesticide * Styptic * Topoisomerase-I-Inhibitor Hamada, S. I., Kataoka, T., Woo, J. T., Yamada, A., Yoshida, T., Nishimura, T., Otake, N., Nagai, K. 1997. Immunosuppressive Effects by Gallic Acid and Chebulagic Acid on CTL-Mediated Cytotoxicity. Biol Pharm Bull, 20: 1017-1019. Xanthine-Oxidase-Inhibitor IC50=24 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
22	ISOQUERCITRIN	Plant	--	--	--	*
ACE-Inhibitor ID50=300 ug/ml rat (24 hr.) * Aldose-Reductase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticancer * Antielastase IC50=0.7 ug/ml * Antifeedant Russell, G. B., Phytochemical resources for crop protection, N. Z. J. Technol., 2, 1986, 127-134. Antiinflammatory * Antinociceptive * Antioxidant 1/4 quercetin * Antioxidant IC50=9.0 uM * Antiradicular 1/4 quercetin * Antitumor * Antitumor-Promoter * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Capillarigenic * Diaphoretic * Diuretic 10 ppm List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979. Hypotensive Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * TNF-alpha-Inhibitor * Topoisomerase-II-Inhibitor 550 ug/ml Bernard, F. X., Sable, S., Cameron, B., Provost, J., Desnottes, J. F., Crouzet, J., Blanche, F. 1997. Glycosylated Flavones as Selective Inhibitors of Topoisomerase IV. Antimicrobial Agents & Chemotherapy, 41: 992-998.
5	ISOVALERIC-ACID	Plant	--	--	--	*
FLavor FEMA 1-16 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Perfumery Merck 11th Edition Sedative * Tranquilizer Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
75	KAEMPFEROL	Plant	--	--	--	*
11B-HSD-Inhibitor * 5-Lipoxygenase-Inhibitor IC50 (uM)=20 * Aldose-Reductase-Inhibitor 100 uM Oliveira, T. T., Nagem, T. J., Miranda, L. C. G., Paula, V. F., Teixeira, M. A. 1997. Inhibitory Action on Aldose Reductase by Soybean Flavonoids. J Braz Chem Soc, 8(3): 211-213. Antiaflatoxin IC50=3.28 ppm * Antiaflatoxin IC50=8.73 uM * Antiaggregant 30 uM * Antiallergic * Antibacterial 20 ug/ml * Anticancer * Antifertility 250 mg/kg/day/60 days/orl rat Kumar, P., Dixit, V.P., and Khanna, P. Antifertility Studies of Kaempferol: Isolation and Identification from Tissue Culture of some Medicinally Important Plant Species. Plantes medicinales et phytotherapie, 23: 193-201, 1989. Antigingivitic 20 ug/ml Antiherpetic 23-92 ug/ml Amoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992. Antihistaminic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiimplantation * Antiinflammatory 20 mg/kg * Antiinflammatory 200 mg/kg ipr rat * Antileukemic IC50=3.1 ug/ml Life Sciences 55: 1061. Antilymphocytic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antimutagenic ID50=10-40 nM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Antioxidant 3/4 quercetin * Antioxidant IC50=1.2 ug/ml * Antioxidant IC50=40 uM * Antiperiodontic 20 ug/ml * Antiplaque 20 ug/ml * Antiradicular 7 x quercetin * Antiseptic 20 ug/ml * Antiserotonin 200 mg/kg ipr rat * Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antistaphylococcic * Antitumor * Antitumor-Promoter Yasukawa, K., Takido, M., Takeuchi, M., Sato, Y., Nitta, K., and Nakagawa, S. 1989. Inhibitory Effects of Flavonol Glycosides on 12-O-Tetradecanoylphorbol-13-acetate-Induced Tumor Promotion. Chem. Pharm. Bull. 38(3): 774-776, 1990. Antiulcer 50-200 mg/kg ipr rat * Antiviral 23-92 ug/ml * Apoptotic 60 uM * Aromatase-Inhibitor IC12=1 uM/l Journal of Medicinal Food 2: 235.1999. cAMP-Phosphodiesterase-Inhibitor * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carcinogenic Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp. Choleretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Copper-Chelator * COX-2-Inhibitor * Cyclooxygenase-Inhibitor IC50 (uM) =20 * Cytotoxic * Diaphoretic? Lawrence Review of Natural Products, Dec-90. Diuretic * Estrogenic EC50=0.1-25 uM/l Journal of Medicinal Food 2: 227.1999. Estrogenic EC50=0.56 uM * Fungicide 20 ug/ml Father Nature's Farmacy: The aggregate of all these three-letter citations. Hepatoprotective IC50=5.46 uM * Hepatoprotective IC50=1.30 ppm * HIV-RT-Inhibitor IC50=50-150 ug/ml Garcia, J., Morin,* C., Nyasse, B., Sondengam, B-L., Tchouankeu, J-C., and Tsamo, E. Complete Structural Assignments Of An Ergosterol Derivative From Entandrophragma utile. Journal of Natural Products, 54(1): 136-142, 1991. Hypotensive * ICAM-1-Inhibitor * iNOS-Inhibitor IC50=<15 uM * iNOS-Inhibitor IC50=13.9 uM * Inotropic * Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. JNK-Inhibitor * Lipoxygenase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. MAO-Inhibitor * Mutagenic * Natriuretic * Neuroprotective * NO-Inhibitor IC50=13.9 uM * PAF-Inhibitor * Pesticide * Protisticide Meckes, M., Calzada, F., Tapia-Contreras, A., Cedillo-Rivera, R. 1999. Antiprotozoal Properties of Helianthemum glomeratum. Phytotherapy Research, 13(2): 102-105. Quinone-Reductase-Inducer 3 uM * Teratologic * TNF-alpha-Inhibitor IC50=3.99 uM * Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237. Topoisomerase-II-Inhibitor IC50=8.1 ug/ml Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225. Tyrosinase-Inhibitor ID50=230 uM * Uterotrophic EC50=0.1-25 uM/l Journal of Medicinal Food 2: 227.1999. Vasodilator *
0	KAEMPFEROL-3-0-GLUCOSIDE	Plant	--	--	--	*

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Melaleuca leucadendra (Myrtaceae)

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