Harpagophytum procumbens | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Devil's Claw, Grapple Plant

How used

Medicinal

Data Views

Activities: 539

Chemicals w/Activities: 84

All Chemicals: 137

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	2-METHOXY-BENZYL ALCOHOL	Tuber	--	--	--	*
0	3-BETA-ACETYL-OLEANOLIC ACID	Root	--	--	--	*
0	4-METHOXY-BENZYL ALCOHOL	Tuber	--	--	--	*
0	6'-O-(P-COUMAROYL)-PROCUMBIDE	Plant	--	--	--	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
0	6'-O-(P-COUMAROYL)-PROCUMBIDE	Root	--	31.3	--	*
0	8-O(P-COUMAROYL)-HARPAGIDE	Plant	--	--	--	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
0	8-O(P-COUMAROYL)-HARPAGIDE	Root	--	184.0	--	*
0	8-P-COUMAROYL-HARPAGIDE	Tuber	--	--	--	*
1	ACETOSIDE	Root	--	--	--	Abstract (See species file)
Aldose-Reductase-Inhibitor IC50=0.4 ppm Kohda, H., Tanaka, S., Yamaoka, Y., Yahara, S., Nohara, T., Tanimoto, T., Tanaka, A. 1989. Studies on Lens-Aldose-Reductase Inhibitor in Medicinal Plants.II Active Constituents of Monochasma savatierii FRANCH, et MAXIM. Chem. Pharm. Bull. 37(11):3153-3154
3	ALANINE	Root	--	60.0	-1.67	*
Antioxidant Larson, R.A. 1987. Review Article Number 30. The Antioxidants of Higher Plants. Phytochemistry. 27: 969-978. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Oxidant Larson, R.A. 1987. Review Article Number 30. The Antioxidants of Higher Plants. Phytochemistry. 27: 969-978.
5	ALUMINUM	Root	178.0	939.0	0.19	*
Antisilicotic Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. Antivaginitic Martindale's 28th Candidicide Martindale's 28th Encephalopathic Martindale's 29th Pesticide *
14	ARGININE	Root	--	840.0	-0.50	*
Antidiabetic? Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Antiencephalopathic Martindale's 29th Antihepatitic Martindale's 29th Antihypertensive * Antiimpotence * Antiinfertility 4 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antioxidant? * Aphrodisiac 3 g/day * Diuretic * Hypoammonemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. NO-Genic * Pituitary-Stimulant * Spermigenic 4 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Vasodilator *
112	ASCORBIC-ACID	Root	--	--	--	*
Acidulant FEMA 6,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Aldose-Reductase-Inhibitor Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Analgesic 5-10 g/day * Angiotensin-Receptor-Blocker * AntiAGE 2,000 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaggregant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaging 400 mg/day * Antiallergic * Antialzheimeran 2,000-6,000 mg/day * Antiarthritic 0.2-1 g/day * Antiasthmatic 1,000 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiatherosclerotic * Antibacterial Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anticataract 1 g 3x/day * Anticataract 350 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticataract 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Anticervicaldysplasic 1,000-2,000 mg/day * AntiCFS 500-1,000 mg * Anticlimacteric 500-5,000 mg/day * Anticold 1-2 g/man/day * AntiCrohn's 50-100 mg/day/orl/man Martindale's 29th AntiCTS 1,000 mg 3x/day * Antidecubitic 500 mg/man/2x/day Martindale's 28th Antidementia * Antidepressant 2,000 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antidiabetic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antidote (Aluminum) Economic & Medicinal Plant Research, 6: 189. Antidote (Cadmium) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Paraquat) Martindale's 28th Antieczemic 3.5-5 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiedemic 1 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiencephalitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiendometriotic 2,000 mg/day * Antifatigue 500-1,000 mg * Antifibrotic 1,000-2,000 mg * Antigallstone 1,000-3,000 mg/day * Antigastritic * Antigingivitic * Antiglaucomic 2 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antihangover 1,000 mg * Antihemorrhagic 1 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihepatitic 2-6 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihepatotoxic Economic & Medicinal Plant Research, 6: 189. Antiherpetic 1-5 g/day * Antihistaminic 2 g/day orl man * Antihypertensive * Antiinfertility 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiinflammatory Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antilepric 1.5 g/man/day Martindale's 28th Antilithic 1,000-3,000 mg/day * AntiLyme 500-2,000 mg * Antimaculitic * Antimeasles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 500-5,000 mg/day * Antimigraine Martindale's 29th Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antineuramidase * Antinitrosic 1 g/man/day Martindale's 28th Antiobesity 1 g 3x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiorchitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiosteoarthritic 1 g 2x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic 500 mg/day * Antioxidant 100 ppm * Antiparkinsonian 1 g 2-3x/day * Antiparotitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiperiodontitic 1 g 2x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antipneumonic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antipodriac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antipoliomyelitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antipyretic Economic & Medicinal Plant Research, 6: 189. Antiradicular Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 AntiRaynaud's 500 mg 1-2x/day * Antiretinotic * Antirheumatic * Antirhinitic 1,000 mg 3x/day * Antiscorbutic 10 mg/man/day Martindale's 28th Antiseptic MIC=3.3-217 mg/ml Martindale's 28th Antiseptic 4-8 g/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antishingles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antispasmodic 500-5,000 mg/day * Antistress 500-1,000 mg * Antisyndrome-X 1-4 g/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antitumor (Gastric) * Antitumor (Lung) * Antiulcer * Antiviral 1-5 g/day * Apoptotic 1-10 mM * Asthma-preventive 1,000 mg/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Beta-Adrenergic Receptor Blocker * Beta-Glucuronidase-Inhibitor 1.5 g/day/man * Calcium-Antagonist * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective * Cold-preventive 1-2 g/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Collagenic * Detoxicant * Diuretic 700 mg/man/orl * Fistula-Preventive Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Hypocholesterolemic 300-1,000 mg/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Hypoglycemic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypotensive 1,000 mg/man/day * Immunomodulator * Immunostimulant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Interferonogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Lithogenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Mucolytic 1 g/woman/day Martindale's 28th Pesticide * Uricosuric 4 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Urinary-Acidulant Martindale's 29th Vasodilator * Vulnerary Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
0	ASH	Root	13490.0	71000.0	0.10	*
3	ASPARTIC-ACID	Root	--	160.0	-1.27	*
Antimorphinic Martindale's 28th Neuroexcitant Martindale's 28th Roborant Merck 11th Edition
0	BETA-(3'-4'-DIHYDROXY-PHENYL)-ETHYL-O-ALPHA-L-RHAMNOPYRANOSYL(1-3)BETA-D-GLUCOPYRANOSIDE	Root	--	--	--	*
53	BETA-CAROTENE	Root	--	--	--	*
Allergenic * Androgenic? Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiacne Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiaging * Antiarthritic * Antiasthmatic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticarcinomic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticervicaldysplasic * Anticoronary 50 mg/man/2 days * Antihyperkeratotic * Antiichythyotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antileukoplakic * Antilipoperoxidant IC71=50 ug/ml * Antilupus 150 mg/man/day/2 mos Martindale's 28th Antimaculitic * Antimastitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antioxidant Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiozenic * Antipapillomic * Antiphotophobic 30-300 mg/man/day Martindale's 29th Antipityriasic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). AntiPMS * Antiporphyric 30-300 mg/man/day Martindale's 28th Antiproliferant Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Antipsoriac Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiradicular Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antirheumatic * Antistress Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antitumor Simon, P.W. Carrots and Other Horticultural Crops as a Source of Provitamin A Carotenes. HortScience, 25(12): 1495, 1990. Antitumor (Breast) IC45=60 ug/ml * Antitumor (CNS) IC43=45 ug/ml * Antitumor (Colon) IC43=45 ug/ml * Antitumor (Lung) IC30=60 ug/ml * Antitumor (Prostate) * Antitumor (Stomach) IC26=45 ug/ml * Antiulcer 15,000-25,000 IU/day * Antiulcer 12 mg 3x/day/man/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antixerophthalmic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Cancer-Preventive 22 ppm Jim Duke's personal files. Chemopreventive * Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. COX-1-Inhibitor IC78=50 ug/ml * COX-2-Inhibitor IC82=50 ug/ml * Gastroprotective * Immunostimulant 180 mg/man/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Interferon-Synergist * Mucogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Phagocytotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Prooxidant 20 ug/g * Thymoprotective Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
47	BETA-SITOSTEROL	Tuber	--	--	--	*
Androgenic * Angiogenic * Anorexic Martindale's 28th Antiadenomic Merck 11th Edition Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Anticancer (Cervix) * Anticancer (Lung) * Antiedemic IC54=320 mg/kg orl * Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * Antileukemic * Antilymphomic * Antimutagenic 250 ug/ml * Antiophidic 2.3 mg mus Economic & Medicinal Plant Research, 5: 363. Antioxidant IC44=10 uM * Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antiprostaglandin 30 mg/day/12 wks * Antiprostatadenomic Merck 11th Edition Antiprostatitic 10-20 mg 3 x/day/orl man * Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Antitumor (Cervix) * Antitumor (Lung) * Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991. Apoptotic * Artemicide LC50=110 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Caspase-8-Inducer * Estrogenic * Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Hepatoprotective * Hypocholesterolemic 9-3,330 mg/man/day/orl Martindale's 28th Hypocholesterolemic 2-6 g/man/day/orl Martindale's 30th Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypolipidemic 2-6 g/day * Pesticide * Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Ulcerogenic 500 mg/kg ipr rat *
0	BIOSIDE	Root	--	--	--	Abstract (See species file)
102	CAFFEIC-ACID	Root	--	--	--	*
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity) Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110. Allergenic * Analgesic * Antiadenoviral Economic & Medicinal Plant Research, 5: 207. Antiaggregant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiaging * Antiatherogenic * Antibacterial * Anticancer * Anticarcinogenic Economic & Medicinal Plant Research, 6: 189. Antidepressant * Antiedemic Economic & Medicinal Plant Research, 6: 189. Antielastase IC50=93 um/l * Antielastase IC50=86 ug/ml (475 uM) * Antiescherichic * Antiflu Economic & Medicinal Plant Research, 5: 207. Antigonadotropic Jim Duke's personal files. Antihemolytic 25 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antihepatoadenomic 200 ppm diet orl mus * Antihepatotoxic * Antiherpetic EC50=>50 ug/ml * Antiherpetic 50 ug/ml * Antihistaminic * AntiHIV EC50=200 ug/ml * Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189. Antihyperthyroid * Antiinflammatory * AntiLegionella * Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antileukotriene * Antimelanogenic * Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18. Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18. Antiophidic * Antioxidant 1/2 BHA * Antioxidant 30 mM * Antioxidant 50 uM * Antioxidant 1.3 x Vit. E * Antioxidant IC57=30 ppm * Antioxidant 1/3 quercetin * Antiperoxidant IC35=200 ug/ml * Antiperoxidant IC50=44 uM Planta Medica, 57: A54, 1991. Antiperoxidant IC85=100 ug/ml * Antiproliferant Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antiprostaglandin * Antiradicular 30 mM * Antiradicular IC50=32-35 uM * Antiradicular 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antiradicular 1/3 quercetin * Antiseptic * Antispasmodic EC50=3.4-15 uM Phytotherapy Research, 4: 73. Antistaphylococcic * Antistomatitic Economic & Medicinal Plant Research, 5: 207. Antisunburn * Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69. Antithyroid Jim Duke's personal files. Antitumor 200 ppm diet orl mus * Antitumor (Skin) * Antitumor-Promoter IC42=10 uM Cancer Research, 48: 5941. Antiulcerogenic * Antivaccinia Economic & Medicinal Plant Research, 5: 207. Antiviral IC50=62.5 ug/ml * Anxiolytic * Calcium-Antagonist IC50=1.2 uM rbt * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carcinogenic 2% (diet) * Chemopreventive * Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Clastogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Co-carcinogenic * Collagen-Sparing * COX-2-Inhibitor IC32=100 uM * Cytoprotective Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Cytotoxic TC50=200 ug/ml * Diuretic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. DNA-Active Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. DNA-Protective * Fungicide MIC=0.4 mg/ml * Hepatocarcinogenic 400 ppm diet orl mus (in the absence of alcohol) * Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 210. Hepatotropic * Histamine-Inhibitor * Immunostimulant * Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994. Leukotriene-Inhibitor * Lipoxygenase-Inhibitor IC50=62-148 uM * Lipoxygenase-Inhibitor IC27=5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. Lyase-Inhibitor IC50=94-164 uM * Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25. Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. Pesticide * Prooxidant * Prostaglandigenic * Sedative 500 mg * Sunscreen IC50=2.5 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC91=5 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC98=25 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Tumorigenic Jim Duke's personal files. Vulnerary Xanthine-Oxidase-Inhibitor IC50=39.21 uM Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Harpagophytum procumbens (Pedaliaceae)

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