Cytisus scoparius | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Scotch Broom

How used

Medicinal

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Activities: 345

Chemicals w/Activities: 18

All Chemicals: 41

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	8-GLYCOSYL-5,7,4'-TRIHYDROXY-3'METHOXYFLAVONE	Plant	--	--	--	*
0	ASH	Seed	--	38000.0	-0.30	*
47	BETA-SITOSTEROL	Seed	--	--	--	*
Androgenic * Angiogenic * Anorexic Martindale's 28th Antiadenomic Merck 11th Edition Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Anticancer (Cervix) * Anticancer (Lung) * Antiedemic IC54=320 mg/kg orl * Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * Antileukemic * Antilymphomic * Antimutagenic 250 ug/ml * Antiophidic 2.3 mg mus Economic & Medicinal Plant Research, 5: 363. Antioxidant IC44=10 uM * Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antiprostaglandin 30 mg/day/12 wks * Antiprostatadenomic Merck 11th Edition Antiprostatitic 10-20 mg 3 x/day/orl man * Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Antitumor (Cervix) * Antitumor (Lung) * Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991. Apoptotic * Artemicide LC50=110 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Caspase-8-Inducer * Estrogenic * Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Hepatoprotective * Hypocholesterolemic 2-6 g/man/day/orl Martindale's 30th Hypocholesterolemic 9-3,330 mg/man/day/orl Martindale's 28th Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypolipidemic 2-6 g/day * Pesticide * Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Ulcerogenic 500 mg/kg ipr rat *
0	CHRYSANTHEMEXANTHIN	Plant	--	--	--	*
10	CYTISINE	Seed	--	--	--	*
Antiinflammatory * Hallucinogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Molluscicide * Nematistat Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Pesticide * Pressor Collins, D.J., Culvenor, C.C.J., Lamberton, J.A., Loder, J.W. and Price, J.R., Plants for Medicines, CSIRO, East Melbourne, Australia, 1990, 303 pp. Psychoactive * Respirastimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Teratogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Toxic Mitchell, J. and Rook, A.J. 1923. Botanical Dermatology: plants and plant products injurious to the skin. Vancouver: Greengrass, 1979. xiii, 787 p.: ill.
20	DOPAMINE	Plant	--	--	--	*
Adrenergic * Antilactagogue * Antimyocontractant * Antineurogenic * Antiparkinsonian * Antiprolactin Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antishock Martindale's 29th Antithyreotropic * Cardiotonic Merck 11th Edition Diuretic * Hypertensive Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp. Inotropic Martindale's 29th Myocontractant 10 uM * Natriuretic * Neurotransmitter Martindale's 29th Priapistic Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705. Sympathomimetic Martindale's 29th Teratogenic CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses Vasoconstrictor Martindale's 29th Vasodilator Martindale's 29th
0	EPININE	Plant	--	--	--	*
30	ESCULETIN	Flower	--	--	--	*
5-Lipoxygenase-Inhibitor IC50=0.1-5 uM * Analgesic * Antiarrhythmic * Antiasthmatic? * Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticapillary-Fragility Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Antidysenteric HerbalGram No. 24, page 37. Antiescherichic * Antiinflammatory IC50=0.1-5 uM * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antipyretic * Antiseptic * Antistaphylococcic * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiodepressant * Choleretic Fitoterapia No.5-1986. Cosmetic * Cytotoxic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Dermatitigenic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Fungicide * Hepatoprotective 6 mg/kg mus * Hypertensive Chemical Constituents of Oriental Herbs (3 diff. books) Lipoxygenase-Inhibitor * Musculotropic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Myorelaxant ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes. Pesticide * Sunscreen IC98=20 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC100=50 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. UV-Screen Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Xanthine-Oxidase-Inhibitor IC52=10 uM *
0	FAT	Seed	--	60000.0	-1.08	*
0	FLAVOXANTHIN	Flower	--	--	--	*
0	FURFUROL	Plant	--	--	--	*
81	GENISTEIN	Flower	--	--	--	*
Abortifacient Cooper-Driver, G. A., Chemical substances in plants toxic to animals, pp. 213-47 in Rechcigl, M., Jr., ed. CRC Handbook of Naturally Occurring Food Toxicants, CRC Press, Boca Raton, 1983, 339 pp. Aldose-Reductase-Inhibitor IC50=10 uM * Alpha-Reductase-Inhibitor IC50=35 uM * Antiaggregant 1-10 ug/ml Medline (post 1990 searches filed in my computer) Antiangiogenic 150 uM * Antiatherosclerotic Journal of Medicinal Food 2: 163.1999. Anticancer (Breast) IC50=2.6-6.7 ug/ml * Anticarcinomic (Breast) IC50=?640 uM Medline (post 1990 searches filed in my computer) Anticlimacteric Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705. Antiendoccytotic 100 ug/ml Medline (post 1990 searches filed in my computer) Antiestrogenic * Antifertility * Antihemolytic * Antiimplantation * Antiinflammatory Journal of Medicinal Food 2: 179.1999. Antiischemic Medline (post 1990 searches filed in my computer) Antileukemic >50 ug/ml (185 uM) * Antileukemic IC50=0.010 ug/ml Life Sciences 55: 1061. Antileukotriene IC50=10-15 uM Medline (post 1990 searches filed in my computer) Antilymphomic * Antimelanomic Medline (post 1990 searches filed in my computer) Antimicrobial * Antimitogenic IC50=12 uM * Antimutagenic ID50=50-100 nM Maga, J.A. Contribution of Phenolic Compounds to Smoke Flavor. Phenolic Compounds in Food and Their Effects on Health, Ch.13. Antineuroblastomic * Antiosteoporotic * Antioxidant Phenolic Compounds in Food and Their Effects on Health, 64. Antiproliferative 5-45 uM * Antiprostatadenomic 8-27 ug/ml Medline (post 1990 searches filed in my computer) Antiprostatitic IC50=35 uM * Antispasmodic IC50=34 uM * Antitumor (Breast) * Antitumor (GI) * Antitumor (Ovary) * Antitumor (Prostate) * Antitumor (Stomach) * Antiulcer? * Antiviral * Apoptotic * Aromatase-Inhibitor IC30=1 uM/l Journal of Medicinal Food 2: 235.1999. Calcium-Antagonist 50 uM gpg * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective Journal of Medicinal Food 2: 163.1999. Catechol-O-Methyltransferase-Inhibitor * Cytotoxic >50 ug/ml (185 uM) Medline (post 1990 searches filed in my computer) Cytotoxic IC89=10 ug/ml Planta Medica, 57: A113, 1991. DOPA-Decarboxylase-Inhibitor * Estrogen-Agonist 0.1-1 uM/l Journal of Medicinal Food 2: 139.1999. Estrogenic EC50=0.1-25 uM/l * Flatulent * Fungicide 2.5 mM Geibel, M. 1994. Sensitivity of the Fungus Cytospora persoonii to the Flavonoids of Prunus cerasus. Phytochemistry. 38(3): 599-601. 1995. Fungicide ED50=50->100 * Fungistat IC34=200 uM * Histidine-Kinase-Inhibitor IC50=110 uM Medline (post 1990 searches filed in my computer) Hypocholesterolemic ED50=0.5 mg/kg * Immunostimulant 2-20 mg/kg orl mus * Lipase-Inhibitor * MAO-Inhibitor IC50=60-140 uM * MAO-Inhibitor IC50=95 * MDR-Inhibitor 200 uM Castro, A. F., Altenberg, G. A. 1997. Inhibition of Drug Transport by Genistein in Multidrug-Resistant Cell Expressing P-Glycoprotein. Biochem Pharmacol, 53(1): 89-93. NADH-Ubiquinone-Oxidoreductase-Inhibitor * Natriuretic * Ornithine-Decarboxylase-Inhibitor * Peroxidase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Phytoalexin Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Pituitary-sensitizer Medline (post 1990 searches filed in my computer) PTK-Inhibitor 10-100 uM * Quinone-Reductase-Inducer IC50=4.6 ug/ml * Topoisomerase-I-Inhibitor IC50=250 ppm * Topoisomerase-I-Inhibitor 1-10 ug/ml Okura, A., Arakawa, H., Oka, H., Yoshinari, T., Monden, Y. 1988. Effect of Genistein on Topoisomerase Activity and on the Growth of [VAL 12]HA-RAS-Transformed NIH 3T3 Cells. Biochem Biophys Res Commun, 157: 183-189. Topoisomerase-II-Inhibitor 2-7.5 ug/ml * Topoisomerase-II-Inhibitor IC50=30 ug/ml Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225. Topoisomerase-II-Inhibitor IC50=1-150 uM * Topoisomerase-II-Inhibitor 20 uM Markovits, J., et al. 1989. Inhibitory Effects of the Tyrosine Kinase Inhibitor Genistein on Mammalian DNA Topoisomerase II. Cancer Research, 49: 5111-5117. Topoisomerase-II-Poison Journal of Medicinal Food 2: 167.1999. Trypanosomastat Medline (post 1990 searches filed in my computer) Tyrosine-Kinase-Inhibitor * Uterotrophic EC50=0.1-25 uM/l * Uterotrophic ED50=0.5 mg/kg * VEGF-Inhibitor *
0	GENISTEIN-7,4'-DI-O-APIOSYLGLUCOSIDE	Seed	--	--	--	*
0	GENISTEIN-7-0-GLUCOSIDE	Flower	--	--	--	*
0	GENISTEINE	Fruit	--	--	--	*
0	GIBBERELLIN-A-35	Plant	--	--	--	*
0	HYDOXYLUPANINE	Seed	--	--	--	*
0	HYDOXYTYRAMINE	Flower	--	--	--	*
30	HYPEROSIDE	Flower	--	--	--	*
Aldose-Reductase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Analgesic * Antiaging * Antibacterial MIC=250-500 ug/ml Planta Medica, 57: A43, 1991. Anticancer * Anticapillary-Fragility Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Antidermatitic * Antielastase IC50=0.15 ug/ml * Antiflu Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980. Antihepatotoxic Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Antiinflammatory 1/4 indomethacin Planta Medica, 57: A131, 1991. Antiischemic * Antinociceptive * Antioxidant IC50=4.6 uM * Antiradicular * Antitussive * Antiviral * Antiwrinkle * Calcium-Antagonist * cAMP-Inhibitor IC50=0.14 mg/ml Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Capillarifortificant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Capillarigenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cyclooxygenase-Activator 100 uM Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Diuretic * Hepatoprotective IC80=30 ug/ml Mayumi Ito (nee Someya), et al. 1990. Hepatoprotective Compounds from Canarium album and Euphorbia nematocypha. Chem. Pharm. Bull. 38(8): 2201-2203, 1990. Hypotensive ivn dog * Pesticide * Tissue-Thromboplastin-Inhibitor IC50=20.8 uM * Xanthine-Oxidase-Inhibitor *
0	ISOSPARTEINE	Flower	--	--	--	*

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Cytisus scoparius (Fabaceae)

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