Cichorium intybus | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Chicory, Succory, Witloof

How used

Food

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Activities: 681

Chemicals w/Activities: 151

All Chemicals: 207

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Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	(11S)-11,13-DIHYDROLACTUCIN	Root	--	--	--	*
0	(11S)-11,13-DIHYDROLACTUCOPICRIN	Root	--	--	--	*
1	11(S),13-DIHYDRO-8-DEOXYLACTUCIN	Root	--	--	--	*
Bitter 1.1 ppm *
1	11(S),13-DIHYDROLACTUCIN	Root	--	--	--	*
Bitter 1.4 ppm *
1	11(S),13-DIHYDROLACTUCOPICRIN	Root	--	--	--	*
Bitter 0.2 ppm *
0	3-GLUCURONIDE-ISORHAMNETIN	Leaf	--	--	--	*
0	3-GLUCURONIDE-ISORHAMNETIN	Plant	--	--	--	*
0	3-O-FERULOYL-QUINIC-ACID	Shoot	--	--	--	*
0	3-O-P-COUMAROYL-QUINIC-ACID	Shoot	--	--	--	*
5	8-DEOXYLACTUCIN	Root	--	17.0	--	*
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Bitter 1.1 ppm * Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
5	8-DEOXYLACTUCIN	Plant	--	--	--	*
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Bitter 1.1 ppm * Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
6	ACETOPHENONE	Root	--	--	--	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antibacterial * Fungicide Tomas-Barberan, F., Iniesta-Sanmartin, E., Tomas-Lorente, F., and Rumbero, A. 1989. Antimicrobial Phenolic Compounds From Three Spanish Helichrysum Species. Phytochemistry. 29(4): 1093-1095. 1990. Hypnotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Perfumery FEMA <10,000 * Pesticide * Soporific Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
32	AESCULETIN	Leaf	--	--	--	*
5-Lipoxygenase-Inhibitor IC50=0.1-5 uM * Aldose-Reductase-Inhibitor IC50=0.74 ug/ml cow Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 Analgesic * Antiarrhythmic * Antiasthmatic? * Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticapillary-Fragility Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Antidysenteric HerbalGram No. 24, page 37. Antiescherichic * Antiinflammatory IC50=0.1-5 uM * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antipyretic * Antiseptic * Antistaphylococcic * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiodepressant * Choleretic Fitoterapia No.5-1986. Cosmetic * Cytotoxic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Dermatitigenic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Fungicide * Hepatoprotective 6 mg/kg mus * Hypertensive Chemical Constituents of Oriental Herbs (3 diff. books) Lipoxygenase-Inhibitor * Musculotropic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Myorelaxant ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes. Pesticide * Prostaglandin-Synthesis-Inhibitor 100 uM rbt Hung, H.C., Lai, M.W., Wang, H.R., Chung, Y.L., Hsieh, L.M., Chen, C.C. 1993. Antiproliferative Effect of Esculetin on Vascular Smooth Muscle Cells: Possible Roles of Signal Transduction Pathways. Eur J Pharmacol, 237(1): 39-44. Sunscreen IC98=20 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC100=50 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. UV-Screen Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Xanthine-Oxidase-Inhibitor IC52=10 uM *
32	AESCULETIN	Plant	--	--	--	*
5-Lipoxygenase-Inhibitor IC50=0.1-5 uM * Aldose-Reductase-Inhibitor IC50=0.74 ug/ml cow Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 Analgesic * Antiarrhythmic * Antiasthmatic? * Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticapillary-Fragility Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Antidysenteric HerbalGram No. 24, page 37. Antiescherichic * Antiinflammatory IC50=0.1-5 uM * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antipyretic * Antiseptic * Antistaphylococcic * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiodepressant * Choleretic Fitoterapia No.5-1986. Cosmetic * Cytotoxic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Dermatitigenic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Fungicide * Hepatoprotective 6 mg/kg mus * Hypertensive Chemical Constituents of Oriental Herbs (3 diff. books) Lipoxygenase-Inhibitor * Musculotropic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Myorelaxant ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes. Pesticide * Prostaglandin-Synthesis-Inhibitor 100 uM rbt Hung, H.C., Lai, M.W., Wang, H.R., Chung, Y.L., Hsieh, L.M., Chen, C.C. 1993. Antiproliferative Effect of Esculetin on Vascular Smooth Muscle Cells: Possible Roles of Signal Transduction Pathways. Eur J Pharmacol, 237(1): 39-44. Sunscreen IC98=20 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC100=50 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. UV-Screen Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Xanthine-Oxidase-Inhibitor IC52=10 uM *
33	AESCULIN	Leaf	--	--	--	*
Aldose-Reductase-Inhibitor 10 ug/ml cow Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 Analgesic * Antiacrocyanotic * Antiaging * Antialopecic * Antiarthritic * Anticapillary-Fragility Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Anticellulitic * AntiCVS * Antidermatitic * Antierythemic 4 mg orl man * Antihemorrhoidal * Antihistaminic * Antiinflammatory * Antioxidant Jim Duke's personal files. Antipanniculopathic * Antipyretic * AntiRaynaud's * Antiseborrheic * Bacteristat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cancer-Preventive Jim Duke's personal files. Cardiotonic * Choleretic Fitoterapia No.5-1986. Cosmetic * Diuretic * Hypertensive * Lipoxygenase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Microvasculokinetic * Sunscreen * Sunscreen IC39=20 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC26=50 mg/l Toxic * Vasoprotective *
33	AESCULIN	Plant	--	--	--	*
Aldose-Reductase-Inhibitor 10 ug/ml cow Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 Analgesic * Antiacrocyanotic * Antiaging * Antialopecic * Antiarthritic * Anticapillary-Fragility Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Anticellulitic * AntiCVS * Antidermatitic * Antierythemic 4 mg orl man * Antihemorrhoidal * Antihistaminic * Antiinflammatory * Antioxidant Jim Duke's personal files. Antipanniculopathic * Antipyretic * AntiRaynaud's * Antiseborrheic * Bacteristat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cancer-Preventive Jim Duke's personal files. Cardiotonic * Choleretic Fitoterapia No.5-1986. Cosmetic * Diuretic * Hypertensive * Lipoxygenase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Microvasculokinetic * Sunscreen * Sunscreen IC39=20 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC26=50 mg/l Toxic * Vasoprotective *
10	ALPHA-AMYRIN	Seed	--	--	--	*
Analgesic * Antiedemic IC43=40 mg/kg ipr rat * Antiinflammatory IC71=1,000 ppm orl * Antinociceptive * Antitumor * Antiulcer * Cytotoxic 50-400 * Gastroprotective * Hepatoprotective * Insectifuge *
0	ALPHA-LACTUCEROL	Plant	--	--	--	*
15	ALPHA-LINOLENIC-ACID	Leaf	60.0	1224.0	-1.06	USDA's Ag Handbook 8 and sequelae)
5-Alpha-Reductase-Inhibitor * Antiaggregant Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp. Antihypertensive * Antiinflammatory IC50=42 uM * Antileukotriene-D4 IC50=42 uM * Antimenorrhagic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antimetastatic Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp. Antiprostatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Hypotensive Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp. Immunostimulant 0.12 ml/man/day Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp. Lymphocytogenic 0.5 ug/ml Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp. Propecic * Prostaglandin-Synthesis-Inhibitor 39.5 g/day/hmn Ferretti, A., Flanagan, V. P. 1996. Antithromboxane Activity of Dietary Alpha-linolenic Acid: A Pilot Study. Prostaglandins Leukotrienes Essential Fatty Acids, 54(6): 451-455. ARS, USDA. Vasodilator *
15	ALPHA-LINOLENIC-ACID	Root	130.0	650.0	-0.32	USDA's Ag Handbook 8 and sequelae)
5-Alpha-Reductase-Inhibitor * Antiaggregant Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp. Antihypertensive * Antiinflammatory IC50=42 uM * Antileukotriene-D4 IC50=42 uM * Antimenorrhagic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antimetastatic Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp. Antiprostatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Hypotensive Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp. Immunostimulant 0.12 ml/man/day Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp. Lymphocytogenic 0.5 ug/ml Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp. Propecic * Prostaglandin-Synthesis-Inhibitor 39.5 g/day/hmn Ferretti, A., Flanagan, V. P. 1996. Antithromboxane Activity of Dietary Alpha-linolenic Acid: A Pilot Study. Prostaglandins Leukotrienes Essential Fatty Acids, 54(6): 451-455. ARS, USDA. Vasodilator *

List of all activity chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Cichorium intybus (Asteraceae)

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