An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. YOHIMBINE

YOHIMBINE

Chemical ID
YOHIMBINE
Ubiquitous
No
List of known dosages
Dosage Reference
LDlo=16 (ivn mus) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LDlo=40 (orl mus) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LDlo=11 (ivn rbt) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LDlo=50 (scu rbt) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.

Select a Results View:

Download these results as:
CSV
EXCEL
PDF
List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Cardiovascular 1 mg/kg ivn rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Cholinergic *
CNS-Depressant 8 mg/kg ivn rbt Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
CNS-Depressant 5 mg/kg scu rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
CNS-Depressant Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
CNS-Stimulant *
Emetic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Hypertensive 5 mg/man orl *
Hypothermic *
MAO-Inhibitor *
MDR-Inhibitor 10 uM Bhat, U. G., et al. 1995. A Structure-Function Relationship Among Reserpine and Yohimbine Analogues in Their Ability to Increase Expression of MDR1 and P-Glycoprotein in a Human Colon Carcinoma Cell Line. Mol Pharmacol, 48(4): 682-689.
Mydriatic Merck 11th Edition
Respirodepressant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Respirostimulant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Rhinorreic 20-30 mg/man *
Sialogogue 0.3 mg/kg ivn rat *
Tremorigenic *
Download these results as:
CSV
EXCEL
PDF
List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Alchornea floribunda Plant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Aspidosperma quebracho-blanco Bark *
Catharanthus lanceus Plant 50000.0 CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
Catharanthus roseus Plant CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
Pausinystalia johimbe Bark *
Rauvolfia serpentina Root *
Rauvolfia vomitoria Plant *