Chemical ID
THEOBROMINE
Ubiquitous
No
Dosage | Reference |
---|---|
LD50=200 (orl cat) | |
LD50=789 mg/kg (ipr mus) | Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. |
LD50=1,356 mg/kg (orl mus) | Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. |
LD50=950 mg/kg (orl rat) | Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. |
Activity | Dosage | Reference |
---|---|---|
Anorexic | not available | Martindale's 28th |
Antiasthmatic | 10 mg/kg/orl/man | Martindale's 29th |
Anticellulitic | not available | Duke, 1992 * |
Arteriodilator | not available | Duke, 1992 * |
Bronchodilator | not available | Merck 11th Edition |
cAMP-Inhibitor | IC50=0.06 mg/ml | Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133. |
cAMP-Phosphodiesterase-Inhibitor | not available | Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). |
Cardiotonic | not available | Merck 11th Edition |
cGMP-Phosphodiesterase-Inhibitor | not available | Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). |
CNS-Stimulant | not available | Duke, 1992 * |
Diuretic | 300-600 mg/man/day | Martindale's 28th |
Emetic | not available | Martindale's 28th |
Fetotoxic | 100 mg/kg | Duke, 1992 * |
Herbicide | IC41=100 ppm | Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. |
Myocardiotonic | not available | Duke, 1992 * |
Myorelaxant | not available | Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
Myostimulant | not available | Martindale's 29th |
Pesticide | not available | Duke, 1992 * |
Stimulant | not available | Duke, 1992 * |
Teratogenic | 100 mg/kg | Duke, 1992 * |
Plant Name | Plant Part | Low Parts Per Million | High Parts Per Million | Standard Deviation | Reference |
---|---|---|---|---|---|
Camellia japonica | Flower | not available | not available | not available | Duke, 1992 * |
Camellia japonica | Leaf | not available | not available | not available | Wealth of India. |
Camellia sinensis | Leaf | 500.0 | 1100.0 | -1.0 | Duke, 1992 * |
Camellia sinensis | Pericarp | not available | not available | not available | Duke, 1992 * |
Camellia sinensis | Flower | not available | not available | not available | Duke, 1992 * |
Camellia sinensis | Seed Coat | not available | not available | not available | Duke, 1992 * |
Camellia sinensis | Seed | not available | not available | not available | Duke, 1992 * |
Camellia sinensis | Stem | not available | not available | not available | Duke, 1992 * |
Camellia sinensis | Anther | not available | not available | not available | Duke, 1992 * |
Coffea arabica | Leaf | not available | not available | not available | Duke, 1992 * |
Coffea arabica | Seed | 18.0 | 20.0 | -0.5 | Duke, 1992 * |
Cola acuminata | Seed | not available | 1000.0 | -0.4 | Duke, 1992 * |
Ilex paraguariensis | Leaf | 960.0 | 5000.0 | 1.0 | Duke, 1992 * |
Paullinia cupana | Seed | 200.0 | 400.0 | -0.5 | Duke, 1992 * |
Theobroma angustifolium | Petiole | 30.0 | 32.0 | -1.2 | Duke, 1992 * |
Theobroma angustifolium | Seed | 330.0 | 368.0 | -0.5 | Duke, 1992 * |
Theobroma angustifolium | Testa | 294.0 | 332.0 | -1.4 | Duke, 1992 * |
Theobroma bicolor | Fruit | 1435.0 | 1468.0 | not available | Duke, 1992 * |
Theobroma bicolor | Petiole | 117.0 | 129.0 | 0.0 | Duke, 1992 * |
Theobroma bicolor | Seed | 1139.0 | 1710.0 | -0.4 | Duke, 1992 * |