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Chemical THEOBROMINE

Chemical ID
THEOBROMINE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=200 (orl cat)
LD50=789 mg/kg (ipr mus) Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=1,356 mg/kg (orl mus) Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=950 mg/kg (orl rat) Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Anorexic not available Martindale's 28th
Antiasthmatic 10 mg/kg/orl/man Martindale's 29th
Anticellulitic not available Duke, 1992 *
Arteriodilator not available Duke, 1992 *
Bronchodilator not available Merck 11th Edition
cAMP-Inhibitor IC50=0.06 mg/ml Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133.
cAMP-Phosphodiesterase-Inhibitor not available Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cardiotonic not available Merck 11th Edition
cGMP-Phosphodiesterase-Inhibitor not available Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
CNS-Stimulant not available Duke, 1992 *
Diuretic 300-600 mg/man/day Martindale's 28th
Emetic not available Martindale's 28th
Fetotoxic 100 mg/kg Duke, 1992 *
Herbicide IC41=100 ppm Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Myocardiotonic not available Duke, 1992 *
Myorelaxant not available Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Myostimulant not available Martindale's 29th
Pesticide not available Duke, 1992 *
Stimulant not available Duke, 1992 *
Teratogenic 100 mg/kg Duke, 1992 *
List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Camellia japonica Flower not available not available not available Duke, 1992 *
Camellia japonica Leaf not available not available not available Wealth of India.
Camellia sinensis Leaf 500.0 1100.0 -1.0 Duke, 1992 *
Camellia sinensis Pericarp not available not available not available Duke, 1992 *
Camellia sinensis Flower not available not available not available Duke, 1992 *
Camellia sinensis Seed Coat not available not available not available Duke, 1992 *
Camellia sinensis Seed not available not available not available Duke, 1992 *
Camellia sinensis Stem not available not available not available Duke, 1992 *
Camellia sinensis Anther not available not available not available Duke, 1992 *
Coffea arabica Leaf not available not available not available Duke, 1992 *
Coffea arabica Seed 18.0 20.0 -0.5 Duke, 1992 *
Cola acuminata Seed not available 1000.0 -0.4 Duke, 1992 *
Ilex paraguariensis Leaf 960.0 5000.0 1.0 Duke, 1992 *
Paullinia cupana Seed 200.0 400.0 -0.5 Duke, 1992 *
Theobroma angustifolium Petiole 30.0 32.0 -1.2 Duke, 1992 *
Theobroma angustifolium Seed 330.0 368.0 -0.5 Duke, 1992 *
Theobroma angustifolium Testa 294.0 332.0 -1.4 Duke, 1992 *
Theobroma bicolor Fruit 1435.0 1468.0 not available Duke, 1992 *
Theobroma bicolor Petiole 117.0 129.0 0.0 Duke, 1992 *
Theobroma bicolor Seed 1139.0 1710.0 -0.4 Duke, 1992 *