Chemical SANGUINARINE | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

SANGUINARINE

Ubiquitous

List of known dosages
Dosage	Reference
LD50=1,658 (orl rat)	Merck 11th Edition
LD50=16-102 (ivn mus)	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp., Merck 11th Edition
LD50=18 (ipr mus)
LD50=292 (ivn rat)
LD50=28.7 (ivn rat)
LD50=>200 (der rat)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
12-Lipoxygenase-Inhibitor	not available	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
5-Lipoxygenase-Inhibitor	not available	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Anesthetic	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiacetylcholinesterase	not available	Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Antibacterial	2 ug/ml	Duke, 1992 *
Anticholinesterase	not available	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiedemic	not available	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antigingivitic	2 ug/ml	Duke, 1992 *
Antiinflammatory	not available	Merck 11th Edition
Antimitotic	not available	Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Antineoplastic	not available	Duke, 1992 *
Antioxidant	IC50=10 uM	Duke, 1992 *
Antiperiodontic	2 ug/ml	Duke, 1992 *
Antiplaque	2 ug/ml	Duke, 1992 *
Antiseptic	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antisuperoxidogenic	IC50=16 nM	Duke, 1992 *
Antitrypanosomic	not available	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Antitumor	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiviral	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Calcium-Antagonist	IC50=15 uM gpg	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Argemone mexicana	Seed	not available	not available	not available	Duke, 1992 *
Bocconia frutescens	Wood	not available	not available	not available	Duke, 1992 *
Chelidonium majus	Plant	not available	not available	not available	Duke, 1992 *
Corydalis spp	Plant	not available	not available	not available	Duke, 1992 *
Eschscholzia californica	Seed	not available	not available	not available	Duke, 1992 *
Eschscholzia californica	Stem	not available	not available	not available	Duke, 1992 *
Eschscholzia californica	Plant	not available	not available	not available	Duke, 1992 *
Eschscholzia californica	Shoot	not available	not available	not available	Duke, 1992 *
Eschscholzia californica	Tissue Culture	1.4	60.0	not available	Duke, 1992 *
Eschscholzia californica	Root	not available	not available	not available	Duke, 1992 *
Eschscholzia californica	Leaf	not available	not available	not available	Duke, 1992 *
Glaucium flavum	Root	not available	not available	not available	Duke, 1992 *
Glaucium flavum	Seed	not available	not available	not available	Duke, 1992 *
Macleaya cordata	Leaf	not available	not available	not available	Duke, 1992 *
Papaver somniferum	Plant	not available	not available	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Papaver somniferum	Tissue Culture	not available	not available	not available	Duke, 1992 *
Papaver somniferum	Root	not available	not available	not available	Duke, 1992 *
Papaver somniferum	Stem	not available	not available	not available	Duke, 1992 *
Papaver somniferum	Leaf	not available	not available	not available	Duke, 1992 *
Sanguinaria canadensis	Root	6000.0	60000.0	not available	Duke, 1992 *