Chemical PROTOPINE

List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)

Activity Sort descending	Dosage	Reference
Abortifacient	70 mg/kg	Duke, 1992 *
Aldose-Reductase-Inhibitor	50 uM	Kubo, M., et al. 1994. Studies on Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in vit Aldose Reductase Activity. Biol Pharm Bull, 17(3): 458-459.
Aldose-Reductase-Inhibitor	IC50=38.5 uM rat	Al-Khalil, S. 1996. Inhibition of Lens Alkaloids Reductase by Protopine Alkaloids. Saudi Pharm J, 4(1): 45-47.
Amphicholeretic	not available	Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Analgesic	not available	Duke, 1992 *
Antiaggregant	100-1,000 uM	Duke, 1992 *
Antiarrhythmic	not available	Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Antibacterial	not available	Duke, 1992 *
Anticholinergic	not available	Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Antiinflammatory	100 mg/kg	Duke, 1992 *
Antiseptic	1,000 ppm	Duke, 1992 *
Antispasmodic	not available	Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Antispermigenic	not available	Duke, 1992 *
Antitussive	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Calcium-Antagonist	not available	Duke, 1992 *
Convulsant	not available	Duke, 1992 *
Gram(+)icide	not available	Duke, 1992 *
Hypertensive	<1 g/kg	Duke, 1992 *
Hypotensive	>1 mg/kg	Duke, 1992 *
Myorelaxant	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.