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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Chemical MYRISTICIN

Chemical ID
MYRISTICIN
Ubiquitous
No
List of known dosages
Dosage Reference
LDlo=570 (orl cat)
LD50=200 mg/kg (ivn mus) Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp., Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=1,000 mg/kg (ipr rat) Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Amphetaminagenic *
Anesthetic *
Antiaggregant IC50=250 uM Janssens, J., Laekeman, G.M., Pieters, L.A.C., Totte, J., Herman, A.G., and Vlietinck, A.J. 1990. Nutmeg Oil: Identification and Quantitation of its Most Active Constituents as Inhibitors of Platelet Aggregation. J.of Ethnopharmacology, 29: 179-188, 1990.
Antidepressant Jim Duke's personal files.
Antiinflammatory Jim Duke's personal files.
Antioxidant 25-100 mg/kg/orl Jim Duke's personal files.
Antispasmodic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antistress ihl Jim Duke's personal files.
Calcium-Antagonist IC50=88 uM *
Calcium-Antagonist IC50=63.1 gpg (weak activity) *
Cancer-Preventive 10 mg/mus/orl/day Jim Duke's personal files.
Diuretic Tyler, V.E.. 1982. The Honest Herbal. George F. Stickley Co., Philadelphia PA. 263 pp.
FLavor FEMA 0.1-10 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide MIC=20 ug *
Hallucinogenic Cooper-Driver, G. A., Chemical substances in plants toxic to animals, pp. 213-47 in Rechcigl, M., Jr., ed. CRC Handbook of Naturally Occurring Food Toxicants, CRC Press, Boca Raton, 1983, 339 pp.
Hepatotoxic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Hypnotic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Hypotensive ihl Jim Duke's personal files.
Insecticide 25 ppm Hostettmann, K., Marston, A., Maillard, M. and Hamburger, M., eds.
1995. Phytochemistry of Plants Used in Traditional Medicine. (Proc. Phytochem. Soc. Eur. 37) Oxford Science Publications. New York. 408 pp.
Insecticide-Synergist Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
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