Chemical METHYSTICIN

Chemical ID

METHYSTICIN

Ubiquitous

No

List of known dosages
Dosage	Reference
LD50=530 mg/kg (ipr mus)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=49 mg/kg (ivn mus)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=>800 mg/kg (orl mus)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Sort descending	Dosage	Reference
Analgesic	360 mg/kg ipr mus	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anesthetic	0.25%	Duke, 1992 *
Anticonvulsant	not available	R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Antidote (Strychnine)	(Strychnine 3 mg/kg) IC=31 mg/kg	Duke, 1992 *
Antifibrillary	20 mg/kg	Duke, 1992 *
Antiinflammatory	not available	CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
Antiischemic	10-30 mg/kg ivn mus	Duke, 1992 *
Antinociceptive	not available	Duke, 1992 *
Antipyretic	not available	CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
Antispasmodic	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
CNS-Depressant	not available	Duke, 1992 *
Endoanesthetic	5-20 mg/kg	Duke, 1992 *
MAO-B-Inhibitor	not available	Duke, 1992 *
Myorelaxant	45 mg/kg	Duke, 1992 *
Neuroprotective	10-30 mg/kg ivn mus	Duke, 1992 *
Neurotoxic	not available	R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Psychoactive	not available	R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Sedative	45 mg/kg ipr	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Sort descending	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Piper methysticum	Resin, Exudate, Sap	not available	22200.0	not available	Duke, 1992 *
Piper methysticum	Plant	not available	not available	not available	Duke, 1992 *
Piper methysticum	Rhizome	12000.0	13400.0	not available	Duke, 1992 *
Piper methysticum	Stem	not available	not available	not available	Duke, 1992 *
Piper methysticum	Leaf	not available	7100.0	not available	Duke, 1992 *
Piper methysticum	Root	not available	140.0	not available	Duke, 1992 *