Chemical GENISTEIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

GENISTEIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Calcium-Antagonist	50 uM gpg	Duke, 1992 *
Cancer-Preventive	not available	Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective	not available	Journal of Medicinal Food 2: 163.1999.
Catechol-O-Methyltransferase-Inhibitor	not available	Duke, 1992 *
Cytotoxic	>50 ug/ml (185 uM)	Medline (post 1990 searches filed in my computer)
Cytotoxic	IC89=10 ug/ml	Planta Medica, 57: A113, 1991.
DOPA-Decarboxylase-Inhibitor	not available	Duke, 1992 *
Estrogen-Agonist	0.1-1 uM/l	Journal of Medicinal Food 2: 139.1999.
Estrogenic	EC50=0.1-25 uM/l	Duke, 1992 *
Flatulent	not available	Duke, 1992 *
Fungicide	2.5 mM	Geibel, M. 1994. Sensitivity of the Fungus Cytospora persoonii to the Flavonoids of Prunus cerasus. Phytochemistry. 38(3): 599-601. 1995.
Fungicide	ED50=50->100	Duke, 1992 *
Fungistat	IC34=200 uM	Duke, 1992 *
Histidine-Kinase-Inhibitor	IC50=110 uM	Medline (post 1990 searches filed in my computer)
Hypocholesterolemic	ED50=0.5 mg/kg	Duke, 1992 *
Immunostimulant	2-20 mg/kg orl mus	Duke, 1992 *
Lipase-Inhibitor	not available	Duke, 1992 *
MAO-Inhibitor	IC50=60-140 uM	Duke, 1992 *
MAO-Inhibitor	IC50=95	Duke, 1992 *
MDR-Inhibitor	200 uM	Castro, A. F., Altenberg, G. A. 1997. Inhibition of Drug Transport by Genistein in Multidrug-Resistant Cell Expressing P-Glycoprotein. Biochem Pharmacol, 53(1): 89-93.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Pueraria montana	Leaf	not available	316.9	-0.9	Kaufman,PB,Duke,JA,Brielmann,H,Boik,J and Hoyt,JE. 1997. A Comparative Survey of Leguminous Plants as Sources of the Isoflavones Genistein and Daidzein: Implications For Human Nutrition and Health. Journal of Alternative & Complementary Medicine 3(1):7-12
Pueraria montana	Leaf Diffusate	not available	3.0	-0.8	Duke, 1992 *
Pueraria montana	Flower	not available	not available	not available	Duke, 1992 *
Pueraria montana	Stem	not available	not available	not available	Duke, 1992 *
Pueraria montana	Leaf Diffusate	not available	3.0	-0.8	Duke, 1992 *
Pueraria phaseoloides	Leaf Diffusate	not available	9.0	-0.2	Duke, 1992 *
Pueraria pseudohirsuta	Root	not available	not available	not available	Chemical Constituents of Oriental Herbs (3 diff. books)
Rhynchosia acuminatifolia	Leaf Diffusate	not available	6.0	-0.5	Duke, 1992 *
Rhynchosia cabibaea	Leaf Diffusate	not available	5.0	-0.6	Duke, 1992 *
Rhynchosia densiflora	Leaf Diffusate	not available	6.0	-0.5	Duke, 1992 *
Rhynchosia hirsuta	Leaf Diffusate	not available	6.0	-0.5	Duke, 1992 *
Rhynchosia minima	Leaf Diffusate	not available	6.0	-0.5	Duke, 1992 *
Rhynchosia phaseoloides	Leaf Diffusate	not available	6.0	-0.5	Duke, 1992 *
Rhynchosia pyramidalis	Leaf Diffusate	not available	10.0	0.0	Duke, 1992 *
Rhynchosia volubilis	Leaf Diffusate	not available	5.0	-0.6	Duke, 1992 *
Sophora japonica	Plant	not available	not available	not available	Duke, 1992 *
Sophora subprostrata	Root	not available	not available	not available	Duke, 1992 *
Spartium junceum	Shoot	not available	not available	not available	Duke, 1992 *
Stauracanthus boivinii	Leaf	not available	not available	not available	Duke, 1992 *
Stauracanthus genistoides	Leaf	not available	not available	not available	Duke, 1992 *