Chemical ID
DIHYDROMETHYSTICIN
Ubiquitous
No
| Dosage | Reference |
|---|---|
| LD50=420 mg/kg (ipr mus) | |
| LD50=67 mg/kg (ivn mus) | Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. |
| LD50=1050 mg/kg (orl mus) | Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. |
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| Activity Sort descending | Dosage | Reference |
|---|---|---|
| Analgesic | not available | Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. |
| Anesthetic | 0.25% | Duke, 1992 * |
| Anticonvulsant | ED50 140 mg/kg orl mus | Duke, 1992 * |
| Antidote (Strychnine) | not available | Duke, 1992 * |
| Antiepileptic | 800 mg/man | Duke, 1992 * |
| Antiinflammatory | not available | Duke, 1992 * |
| Antiischemic | 10-30 mg/kg ivn mus | Duke, 1992 * |
| Antinociceptive | not available | Duke, 1992 * |
| Antipyretic | not available | Duke, 1992 * |
| Antispasmodic | not available | Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
| CNS-Depressant | not available | Duke, 1992 * |
| Dermatitigenic | not available | Duke, 1992 * |
| Endoanesthetic | 5-20 mg/kg | Duke, 1992 * |
| MAO-B-Inhibitor | not available | Duke, 1992 * |
| Myorelaxant | 60 mg/kg | Duke, 1992 * |
| Myorelaxant | IC50 20 mg/kg ivn mus | Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. |
| Neuroprotective | 10-30 mg/kg ivn mus | Duke, 1992 * |
| Sedative | 60 mg/kg ipr | Duke, 1992 * |
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| Plant Name Sort descending | Plant Part | Low Parts Per Million | High Parts Per Million | Standard Deviation | Reference |
|---|---|---|---|---|---|
| Piper methysticum | Plant | not available | not available | not available | Duke, 1992 * |
| Piper methysticum | Leaf | not available | not available | not available | Duke, 1992 * |
| Piper methysticum | Stem | not available | not available | not available | Duke, 1992 * |
| Piper methysticum | Rhizome | 5000.0 | 8500.0 | not available | Duke, 1992 * |
| Piper methysticum | Root | not available | 160.0 | not available | Duke, 1992 * |