Chemical DIHYDROMETHYSTICIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Dr. Duke's Phytochemical and Ethnobotanical Databases

U.S. Department of Agriculture

Chemical ID

DIHYDROMETHYSTICIN

Ubiquitous

No

List of known dosages
Dosage	Reference
LD50=420 mg/kg (ipr mus)
LD50=67 mg/kg (ivn mus)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=1050 mg/kg (orl mus)	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Analgesic	not available	Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anesthetic	0.25%	Duke, 1992 *
Anticonvulsant	ED50 140 mg/kg orl mus	Duke, 1992 *
Antidote (Strychnine)	not available	Duke, 1992 *
Antiepileptic	800 mg/man	Duke, 1992 *
Antiinflammatory	not available	Duke, 1992 *
Antiischemic	10-30 mg/kg ivn mus	Duke, 1992 *
Antinociceptive	not available	Duke, 1992 *
Antipyretic	not available	Duke, 1992 *
Antispasmodic	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
CNS-Depressant	not available	Duke, 1992 *
Dermatitigenic	not available	Duke, 1992 *
Endoanesthetic	5-20 mg/kg	Duke, 1992 *
MAO-B-Inhibitor	not available	Duke, 1992 *
Myorelaxant	60 mg/kg	Duke, 1992 *
Myorelaxant	IC50 20 mg/kg ivn mus	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Neuroprotective	10-30 mg/kg ivn mus	Duke, 1992 *
Sedative	60 mg/kg ipr	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Piper methysticum	Plant	not available	not available	not available	Duke, 1992 *
Piper methysticum	Leaf	not available	not available	not available	Duke, 1992 *
Piper methysticum	Stem	not available	not available	not available	Duke, 1992 *
Piper methysticum	Rhizome	5000.0	8500.0	not available	Duke, 1992 *
Piper methysticum	Root	not available	160.0	not available	Duke, 1992 *