Chemical BAICALEIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

BAICALEIN

Ubiquitous

No

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
12-Lipoxygenase-Inhibitor	not available	Duke, 1992 *
17-beta-hydroxysteroid dehydrogenase-Inhibitor	9.3 uM	Duke, 1992 *
5-Lipoxygenase-Inhibitor	IC50=0.1-5 uM	Duke, 1992 *
Aldose-Reductase-Inhibitor	IC62=10 uM	Shimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Aldose-Reductase-Inhibitor	IC50=0.98 rbt	Kohda, H., Tanaka, S., Yamaoka, Y., Yahara, S., Nohara, T., Tanimoto, T., Tanaka, A. 1989. Studies on Lens-Aldose-Reductase Inhibitor in Medicinal Plants.II Active Constituents of Monochasma savatierii FRANCH, et MAXIM. Chem. Pharm. Bull. 37(11):3153-3154
Aldose-Reductase-Inhibitor	IC50=0.98 ppm	Kohda, H., Tanaka, S., Yamaoka, Y., Yahara, S., Nohara, T., Tanimoto, T., Tanaka, A. 1989. Studies on Lens-Aldose-Reductase Inhibitor in Medicinal Plants.II Active Constituents of Monochasma savatierii FRANCH, et MAXIM. Chem. Pharm. Bull. 37(11):3153-3154
Antiacne	not available	Duke, 1992 *
Antiaggregant	ED50=120-200 mg/kg	Butenko, I.G., Gladtchenko, S.V., and Galushko, S.V. Anti-inflammatory properties and inhibition of leukotriene C4 biosynthesis in vitro by flavonoid baicalein from Scutellaria baicalensis georgy roots. Agents Actions 39: C49, 1993.
Antiallergic	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiarthritic	IC28=20 mg/kg scu rat	Duke, 1992 *
Antiasthmatic	not available	Duke, 1992 *
Antiatherosclerotic	IC50=3.5-8.6 uM	Duke, 1992 *
Antibacterial	not available	Foster, S. and Yue, C-G. 1992. Herbal Emissaries-Bringing Chinese Herbs to the West. Healing Arts Press, Rochester VT. 356 pp.
Anticolitic	20 mg/kg	Duke, 1992 *
Antidermatitic	not available	Duke, 1992 *
Antidote (Strychnine)	10 mg mus	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiedemic	IC28=20 mg/kg scu rat	Duke, 1992 *
Antiflu	not available	Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antigenotoxic	IC50=22-34 uM	Duke, 1992 *
Antihepatomic	not available	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Plantago major	Leaf	not available	not available	not available	Duke, 1992 *
Pueraria montana	Root	not available	not available	not available	Duke, 1992 *
Scutellaria baicalensis	Stem	not available	400.0	not available	Duke, 1992 *
Scutellaria baicalensis	Root	1000.0	54000.0	not available	Duke, 1992 *
Scutellaria galericulata	Plant	not available	not available	not available	Abstract (See species file)
Scutellaria sp	Leaf	not available	not available	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Terminalia arjuna	Stem Bark	not available	8.3	not available	Sharma, P. N., Shoeb, A., Kapil, R. S., Popli, S. P. 1982. Arjunolone-A New Flavone from Stem Bark of Terminalia arjuna. Indian J. Chem. 21B: 263-264.