Chemical APIGENIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

APIGENIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Ornithine-Decarboxylase-Inhibitor	not available	Duke, 1992 *
P21-Inducer	10-70 uM	Duke, 1992 *
Pesticide	not available	Duke, 1992 *
PKC-Inhibitor	IC50=10 uM	Duke, 1992 *
Polyamine-Synthesis-Inhibitor	not available	Duke, 1992 *
Progestational	not available	Duke, 1992 *
Protein-Kinase-C-Inhibitor	IC50=10-40 uM	Duke, 1992 *
PTK-Inhibitor	10-100 uM	Duke, 1992 *
Quinone-Reductase-Inducer	20 uM	Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Radioprotective	not available	Duke, 1992 *
Sedative	30-100 mg/kg	Duke, 1992 *
Sunscreen	not available	Duke, 1992 *
TNF-alpha-Inhibitor	IC50=3.27 uM	Duke, 1992 *
Topoisomerase-I-Inhibitor	not available	Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor	IC28=18 uM	Duke, 1992 *
Topoisomerase-II-Inhibitor	IC45=180 uM	Duke, 1992 *
Topoisomerase-II-Inhibitor	50 ug/ml	Azuma, Y., Onishi, Y., Sato, Y., Kizaki, H. 1995. Effects of Protein Tyrosine Kinase Inhibitors With Different Modes of Action on Topoisomerase Activity and Death of IL-2-Dependent CTLL-2-Cells. J Biochemistry, 118: 312-318.
Uterotrophic	EC50=0.1-25 uM/l	Journal of Medicinal Food 2: 227.1999.
Vasodilator	not available	Duke, 1992 *
VEGF-Inhibitor	IC50=2-7 uM	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Euphrasia officinalis	Plant	not available	not available	not available	Duke, 1992 *
Ginkgo biloba	Pollen Or Spore	not available	109.0	not available	Jim Duke's personal files.
Ginkgo biloba	Leaf	not available	not available	not available	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Glechoma hederacea	Plant	not available	not available	not available	Jim Duke's personal files.
Glycyrrhiza glabra	Root	not available	not available	not available	Duke, 1992 *
Hydnocarpus wightiana	Seed	not available	not available	not available	Duke, 1992 *
Jatropha gossypifolia	Leaf	not available	not available	not available	Duke, 1992 *
Juniperus communis	Plant	not available	not available	not available	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Linum usitatissimum	Plant	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Lycopodium clavatum	Plant	not available	not available	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Maclura pomifera	Fruit	not available	5.0	not available	Duke, 1992 *
Maclura pomifera	Tissue Culture	not available	not available	not available	Duke, 1992 *
Malus domestica	Heart Wood	not available	not available	not available	Duke, 1992 *
Marrubium vulgare	Shoot	not available	not available	not available	Duke, 1992 *
Marrubium vulgare	Leaf	not available	not available	not available	Duke, 1992 *
Marrubium vulgare	Plant	not available	not available	not available	Lawrence Review of Natural Products, Jun-88.
Matricaria recutita	Flower	6.0	8400.0	not available	Tramil
Matricaria recutita	Plant	not available	not available	not available	Duke, 1992 *
Medicago sativa	Shoot	not available	70.0	1.0	Duke, 1992 *
Mentha aquatica	Plant	not available	not available	not available	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.