Chemical APIGENIN

List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)

Activity Sort descending	Dosage	Reference
Ornithine-Decarboxylase-Inhibitor	not available	Duke, 1992 *
P21-Inducer	10-70 uM	Duke, 1992 *
Pesticide	not available	Duke, 1992 *
PKC-Inhibitor	IC50=10 uM	Duke, 1992 *
Polyamine-Synthesis-Inhibitor	not available	Duke, 1992 *
Progestational	not available	Duke, 1992 *
Protein-Kinase-C-Inhibitor	IC50=10-40 uM	Duke, 1992 *
PTK-Inhibitor	10-100 uM	Duke, 1992 *
Quinone-Reductase-Inducer	20 uM	Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Radioprotective	not available	Duke, 1992 *
Sedative	30-100 mg/kg	Duke, 1992 *
Sunscreen	not available	Duke, 1992 *
TNF-alpha-Inhibitor	IC50=3.27 uM	Duke, 1992 *
Topoisomerase-I-Inhibitor	not available	Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor	50 ug/ml	Azuma, Y., Onishi, Y., Sato, Y., Kizaki, H. 1995. Effects of Protein Tyrosine Kinase Inhibitors With Different Modes of Action on Topoisomerase Activity and Death of IL-2-Dependent CTLL-2-Cells. J Biochemistry, 118: 312-318.
Topoisomerase-II-Inhibitor	IC28=18 uM	Duke, 1992 *
Topoisomerase-II-Inhibitor	IC45=180 uM	Duke, 1992 *
Uterotrophic	EC50=0.1-25 uM/l	Journal of Medicinal Food 2: 227.1999.
Vasodilator	not available	Duke, 1992 *
VEGF-Inhibitor	IC50=2-7 uM	Duke, 1992 *