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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. 1,8-CINEOLE

1,8-CINEOLE

Chemical ID
18CINEOLE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=2,480 (orl rat) Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
LD50=3,480 mg/kg
LD50=>5,000 (dml rbt)
LD100=1,000 ug/ml
LD50=100 mg/kg (ims mus) Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 1-200 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide *
Gastroprotective *
Gram(+)icide *
Gram(-)icide *
Hepatotonic *
Herbicide IC50=78 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypotensive *
Inflammatory inj *
Insectifuge *
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Neurotoxic *
P450-Inducer *
Pediculicide 2.3 x pyrethrin *
Perfume Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide *
Rubefacient Martindale's 29th
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Teucrium micropodioides Leaf 12.0 -0.5 Arnold, N., Bellomaria, B., Velentini G. and Rafaiani, S.M. 1991. Comparative Study on Essential Oil of Some Teucrium Species from Cyprus. J. Ethnopharm. 35: 105-113.
Teucrium oxylepis Shoot 1.0 -0.1 Velasco-Negueruela, A. and Perez-Alonso, M.J. 1990. The Volatiles of Six Teucrium Species from the Iberian Peninsula and the Balearic Islands. Phytochemistry 29(4): 1165-9.
Teucrium oxylepis Shoot 1.8 -0.1 Velasco-Negueruela, A. and Perez-Alonso, M.J. 1990. The Volatiles of Six Teucrium Species from the Iberian Peninsula and the Balearic Islands. Phytochemistry 29(4): 1165-9.
Teucrium polium Shoot 1.0 -0.1 Perez-Alonso, M.J. Velasco-Negueruela, A. and Lopez-Saez, J.A. 1993. The Essential Oils of Two Iberian Teucrium Species. J. Ess. Oil Res. 5: 397-402.
Teucrium pseudoscorodonia Shoot 0.3 -0.1 Velasco-Negueruela, A. and Perez-Alonso, M.J. 1990. The Volatiles of Six Teucrium Species from the Iberian Peninsula and the Balearic Islands. Phytochemistry 29(4): 1165-9.
Teucrium salviastrum Shoot 1.0 -0.1 Velasco-Negueruela, A. and Perez-Alonso, M.J. 1990. The Volatiles of Six Teucrium Species from the Iberian Peninsula and the Balearic Islands. Phytochemistry 29(4): 1165-9.
Teucrium scorodonia Shoot 0.5 -0.1 Velasco-Negueruela, A. and Perez-Alonso, M.J. 1990. The Volatiles of Six Teucrium Species from the Iberian Peninsula and the Balearic Islands. Phytochemistry 29(4): 1165-9.
Thymus capitatus Shoot 0.0 -0.1 Biondi, D., Cianci, P., Geraci, C. and Ruberto, G. 1993. Antimicrobial Activity and Chemical Composition of Essential Oils from Sicilian Aromatic Plants. Flav. & Frag. J. 8: 331-7.
Thymus capitatus Plant 10.0 30.0 -0.6 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Thymus cilicicus Shoot 1515.0 -0.1 Tumen, G., Koyuncu, M., Kirimer, N., and Baser, K.H.C. 1994. Composition of the Essential Oil of Thymus cilicicus Boiss. & Bal. J. Ess. Oil Res. 6: 97-8.
Thymus funkii Shoot 1960.0 -0.1 Vila, R., et al. 1995. Composition and study of the variability of the essential oil of Thymus funkii Cousson. Flav. & Fragr. J. 10(6): 379-383.
Thymus funkii Shoot 2200.0 -0.1 Vila, R., et al. 1995. Composition and study of the variability of the essential oil of Thymus funkii Cousson. Flav. & Fragr. J. 10(6): 379-383.
Thymus longicaulis Shoot 0.8 -0.1 Baser, K.H.C., Ozek, T., Kirimer, N. and Tumen, G. 1993. The Occurrence of Three Chemotypes of Thymus longicaulis C. Presl subsp. longicaulis in the same Population. J. Ess. Oil Res. 5: 291-5.
Thymus longicaulis Shoot 24.0 -0.1 Baser, K.H.C., Ozek, T., Kirimer, N. and Tumen, G. 1993. The Occurrence of Three Chemotypes of Thymus longicaulis C. Presl subsp. longicaulis in the same Population. J. Ess. Oil Res. 5: 291-5.
Thymus longicaulis Shoot 0.8 -0.1 Baser, K.H.C., Ozek, T., Kirimer, N. and Tumen, G. 1993. The Occurrence of Three Chemotypes of Thymus longicaulis C. Presl subsp. longicaulis in the same Population. J. Ess. Oil Res. 5: 291-5.
Thymus mastichina Plant 300.0 7500.0 1.5 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Thymus serpyllum Plant 1.0 38.0 -0.6 *
Thymus x citriodorus Plant 50.0 -0.5 Stahl-Biskup, E. and Holthuijzen, J. 1995. Essential oil and glycosidally bound volatiles of lemon-scented thyme, Thymus x citriodorus (Pers.) Schreb. Flav. & Fragr. J. 10: 225-229.
Thymus zygis Shoot 0.1 2000.0 -0.1 De Cunha, A.P. and Salguiero, L.R. 1991. The Chemical Polymorphism of Thymus zygis ssp. sylvestris from Central Portugal. J. Ess. Oil Res. 3: 409-12.
Thymus zygis Shoot 0.1 -0.1 Jimenez, J., Navarro, M.C., Montilla, M.P., Martin, A. and Martinez, A. 1993. Thymus zygis Oil: Its Effects on CCl4-Induced Hepatotoxicity and Free Radical Scavenger Activity. JEO5: 153-8.