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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Cytotoxic

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
PULCHELLIN ED50=1-2 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
PULVEROCHROMENOL *
PUNICIC-ACID *
QUADRIGEMINE EC100=8uM *
QUADRIGENIN *
QUASSIMARIN 1-4,000 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
QUERCETAGETIN-6,7,3',4'-TETRAMETHYLETHER *
QUERCETIN ED50=70 ug/ml Matsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
QUERCETIN IC82=100 ug/ml Planta Medica, 57: A113, 1991.
QUINICINE IC50=3.2 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUINIDINONE IC50=17.7 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUININE IC50=183 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
RADIATIN 0.39 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
RETUSIN ED50=>25 ug/ml Arisawa, M., Hayashi, T., Shimizu, M., Morita, N., Bai, H., Kuze, S., and Ito, Y. Isolation And Cytotoxicity Of Two New Flavonoids From Chrysosplenium grayanum And Related Flavonols. J. Natural Products, 54(3): 898-901, 1991.
RHEIN CD50=3.4 ug/ml *
RHOEADINE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ROBUSTAFLAVONE-4'-METHYL-ETHER Lin, L., Kuo, Y., Chou, C. 2000. Cytotoxic Biflavonoids from Selaginella delicatula. J. Natural Products, 63(5): 627-630.
ROLLINIASTATIN-1 9PS ED50=0.000045 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ROLLINIASTATIN-2 9PS ED50=0.00023 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ROLLINICIN 9PS ED50=0.000000029 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Collinsonia canadensis Stone Root 1 0
Cologana broussonetii 1 0
Colubrina granulosa 1 0
Combretum imberbe 1 0
Commelina communis Common dayflower 1 0
Commiphora myrrha Myrrh; African Myrrh; Herabol Myrrh; Somali Myrrh; Myrrhe (Fr., Ger.); Mirra (Sp. It.) 2 13, 800
Commiphora wightii Guggul; Indian Bdellium-Tree 2 0
Comptonia peregrina 1 0
Conium maculatum Poison Hemlock; Hemlock; Spotted Hemlock; Fool's Parsley; Carrot Fern; Spotted Parsley 1 0
Consolida ajacis Larkspur 2 0
Convallaria majalis Lily-Of-The-Valley 1 0
Conyza canadensis Butterweed; Hogweed; Horseweed 5 0
Coptis chinensis Chinese Goldthread; Huang-Lian; Huang-Lien 1 270, 000
Coptis japonica Huang-Lia; Huang-Lian; Huang-Lien; Japanese Goldthread 1 280, 000
Coptis spp Generic Goldthread 2 90, 000
Coriandrum sativum Coriander; Chinese Parsley; Cilantro 9 3, 964, 008
Coriaria myrtifolia Mealy Tree 3 0
Coriaria thymifolia Ground Toot; Shanshi 3 0
Cornus capitata 2 343.20000648498535
Cornus florida American Dogwood 5 80, 000