Biological Activity COX-2-Inhibitor

List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)

Chemical Name Sort descending	Dosage	Reference
CIRSIMARITIN	IC>50=1,000 uM	Duke, 1992 *
CURCUMIN	10-20 uM	Duke, 1992 *
CYANIDIN-3-O-GLUCOSIDE	IC59=100 ug/ml	Duke, 1992 *
EICOSAPENTAENOIC-ACID	1 uM	Duke, 1992 *
EMODIN	not available	Duke, 1992 *
EUGENOL	IC>97=1,000 uM	Duke, 1992 *
EUGENOL	IC50=129 uM	Duke, 1992 *
EVODIAMINE	2.5 ug/ml	Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
EVODOL	2.5 ug/ml	Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
FLAVOKAWAIN-B	IC16=100 ug/ml	Duke, 1992 *
HUMULONE	not available	Yamamoto, Wang, et al. 2000. Federation of European Biochemical Societies. (per e-mail with Tom Newmark)
ISOTHYMONIN	IC>37=1,000 uM	Duke, 1992 *
KAEMPFEROL	not available	Duke, 1992 *
LAURIC-ACID	IC20=100	Duke, 1992 *
MELATONIN	not available	Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
MYRICETIN-3-O-BETA-D-GLUCURONIDE	IC50=8 uM/	Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
OLEANOLIC-ACID	IC50=295 uM/	Duke, 1992 *
OLEANOLIC-ACID	not available	Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
PARTHENOLIDE	not available	Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
PINOSTROBIN	IC7=100 ug/ml	Duke, 1992 *