An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Biological Activity Antimalarial

List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
ARTEMISININ ED50=90 mg/kg orl mus Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTEMISININ ED95=1,000 mg/man/day Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTEMISININ IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day) Duke, 1992 *
ARTESUNATE not available Duke, 1992 *
ASCARIDOLE 0.05-0.1 uM Duke, 1992 *
ASIMICIN IC50=4 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ATALAPHILLININE 50 mg/kg/day ipr mus Duke, 1992 *
ATAPHILLININE 50 mg/kg (ipr mus) Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
AUGUSTINE IC50=0.14-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
AZADIRADIONE IC50=3 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
AZADIRONE IC50=12 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
BEBEERINE not available Merck 11th Edition
BENZOISOQUINOLONE-5-10-DIONE IC50=0.84 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BERBERASTINE 50 uM Duke, 1992 *
BERBERASTINE 0.14-0.36 ug/ml Duke, 1992 *
BERBERINE 0.14-0.36 ug/ml Duke, 1992 *
BERBERINE 50 uM Duke, 1992 *
BETA-DICHROINE not available Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
BETA-SELINENE IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BETA-SELININE-HYDROPEROXIDE 5.6 ug/ml Duke, 1992 *
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Agastache foeniculum Giant Hyssop 1 0
Agastache nepetoides not available 1 0
Agastache rugosa not available 3 301.80000019073486
Agathosma betulina Buchu; Honey Buchu; Mountain Buchu 3 0
Ageratum conyzoides Mexican ageratum 2 32
Agrimonia eupatoria Agrimony; Sticklewort 4 15, 400
Ailanthus altissima Stinktree; Tree Of Heaven 3 0
Ailanthus grandis not available 1 86
Ajuga remota Bugle 1 500
Akania luceus not available 1 400
Akebia quinata Chocolate Vine 1 0
Alangium lamarckii not available 4 0
Albizia lebbeck East Indian Walnut; Siris Tree; Frywood; Koko; Lebbek; Lebbek Tree; Women's-Tongue Tree 3 0
Aleurites fordii Tungoil Tree 1 0
Aleurites montana not available 1 60
Alisma plantago-aquatica Mud Plantain; Tse-Hsieh; Water Plantain; Ze-Xie 1 0
Allium cepa Onion; Shallot 3 124, 200
Allium sativum var. sativum Garlic 4 200
Allium schoenoprasum Chives 1 9
Alnus glutinosa Black Alder 1 0