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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
AJUGARIN-I IC50=23 uM *
AKAGERINE IC50=7 mg/ml Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
AKUAMMIDINE IC50=0.08-0.9 ug/ml Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
AKUAMMIGINE *
AKUAMMINE (1/500th chloroquine) 1 mg/kg Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
ALPHA-CYPERONE IC50=5.5 ug/ml *
ALPHA-CYPERONE 5.5 ug/ml *
ALPHA-PEROXYACHIFOLIDE IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALPHA-SELINENE IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALPHA-YOHIMBINE IC50=>200 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALPINUMISOFLAVONE IC50=24.6 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
ALSTOMACROLINE IC50=1.1-10.2 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTOMACROPHYLLINE IC50=1.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTONERINE IC50=9.7-46.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTONERINE IC50=46.3 uM *
ALSTOPHYLLINE IC50=12.7-82.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTOUMERINE IC50=13.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBERTSONINE-A IC50=15.9->23.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBERTSONINE-B IC50=9->23.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBERTSONINE-C IC50=4.5-10.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Eupatorium triplinerve Triplinerved eupatorium 1 0
Euphorbia hirta Queensland Asthma Herb 2 0
Euphorbia lathyris Caper Spurge; Mole Plant 1 0
Euphorbia pulcherrima Poinsettia 1 0
Euphorbia tirucalli Aveloz 1 0
Euphrasia officinalis Eyebright 2 0
Euptelea polyandra 1 240
Eurya acuminata 1 18, 000
Eurya japonica 1 0
Fagonia indica 1 0
Fagopyrum esculentum Buckwheat 2 247, 854
Fagus taurica 1 0
Fallopia japonica Japanese Knotweed; Giant Knotweed; Mexican Bamboo; Hu-Zhang 1 0
Ficus carica Fig; Figuier Commun (Fr.); Echte Feige (Ger.); Feigenbaum (Ger.); Fico (Ital.); Figueira (Port.); Higo (Sp.); Higuera Comun (Sp.) 5 114, 400
Ficus thunbergii 1 31.399999618530273
Filipendula ulmaria Meadowsweet; Queen Of The Meadow 2 0
Foeniculum vulgare Fennel 3 0
Formosia benthamiana 1 0
Forsythia suspensa Lian-Jiao; Lien-Chiao 5 2, 000
Forsythia viridissima 1 0