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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
AJUGARIN-I IC50=23 uM *
AKAGERINE IC50=7 mg/ml Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
AKUAMMIDINE IC50=0.08-0.9 ug/ml Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
AKUAMMIGINE *
AKUAMMINE (1/500th chloroquine) 1 mg/kg Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
ALPHA-CYPERONE 5.5 ug/ml *
ALPHA-CYPERONE IC50=5.5 ug/ml *
ALPHA-PEROXYACHIFOLIDE IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALPHA-SELINENE IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALPHA-YOHIMBINE IC50=>200 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALPINUMISOFLAVONE IC50=24.6 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
ALSTOMACROLINE IC50=1.1-10.2 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTOMACROPHYLLINE IC50=1.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTONERINE IC50=9.7-46.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTONERINE IC50=46.3 uM *
ALSTOPHYLLINE IC50=12.7-82.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTOUMERINE IC50=13.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBERTSONINE-A IC50=15.9->23.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBERTSONINE-B IC50=9->23.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBERTSONINE-C IC50=4.5-10.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Diospyros sylvatica 1 0
Diospyros thwaitesii 1 480
Diospyros tomentosa 1 0
Diospyros verrucosa 1 13, 950
Diospyros virginiana American Persimmon 1 0
Diospyros walkeri 1 1, 000
Diospyros wallichii 1 0
Diospyros zenkeri 1 706.7000122070312
Dipterocarpus glandulosus 1 0
Dipterocarpus hispidus 1 140
Dipterocarpus insignis 1 0
Dipterocarpus zeylanicus 1 0
Dipteryx odorata Tonka Bean; Dutch Tonka Bean 1 0
Discaria longispina 1 0
Dodonaea viscosa Hopwood 2 0
Drimys winteri Winter's Bark 1 0
Duboisia myoporoides Corkwood Tree; Pituri 1 20
Duchesnea indica False Strawberry; Indian Strawberry; Mock Strawberry 3 943.8000000715256
Echinacea angustifolia Echinacea; Narrow Leaf Echinacea; Narrow Leaf Purple-Coneflower 1 0
Echinacea purpurea Echinacea; Eastern Purple-Coneflower; Purple-Coneflower 2 0